Structure–Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH)

by Quentin Spillier, Séverine Ravez, Judith Unterlass, Cyril Corbet, Charline Degavre, Olivier Feron, Raphaël Frédérick
Published 2020-01-01

Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments

by Quentin Spillier, Séverine Ravez, Simon Dochain, Didier Vertommen, Léopold Thabault, Olivier Feron, Raphaël Frédérick
Published 2021-01-01