Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

by Caroline Chandra Tjin, Kate D. Otley, Tyler D. Baguley, Pradeep Kurup, Jian Xu, Angus C. Nairn, Paul J. Lombroso, Jonathan A. Ellman
Published 2017-12-01

High Fructose Corn Syrup-Moderate Fat Diet Potentiates Anxio-Depressive Behavior and Alters Ventral Striatal Neuronal Signaling

by Ayanabha Chakraborti, Christopher Graham, Sophie Chehade, Bijal Vashi, Alan Umfress, Pradeep Kurup, Benjamin Vickers, H. Alexander Chen, Rahul Telange, Taylor Berryhill, William Van Der Pol, Mickie Powell, Stephen Barnes, Casey Morrow, Daniel L. Smith, M. Shahid Mukhtar, Stephen Watts, Gregory Kennedy, James Bibb
Published 2021-05-01

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

by Jian Xu, Manavi Chatterjee, Tyler D Baguley, Jonathan Brouillette, Pradeep Kurup, Debolina Ghosh, Jean Kanyo, Yang Zhang, Kathleen Seyb, Chimezie Ononenyi, Ethan Foscue, George M Anderson, Jodi Gresack, Gregory D Cuny, Marcie A Glicksman, Paul Greengard, TuKiet T Lam, Lutz Tautz, Angus C Nairn, Jonathan A Ellman, Paul J Lombroso
Published 2014-08-01