Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response compo...

by Paula Lindner, Søren Brøgger Christensen, Poul Nissen, Jesper Vuust Møller, Nikolai Engedal
Published 2020-01-01

Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

by Tina Skjørringe, Per Amstrup Pedersen, Sidsel Salling Thorborg, Poul Nissen, Pontus Gourdon, Lisbeth Birk Møller
Published 2017-04-01

Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

by Rune Thomas Kidmose, Jonathan Juhl, Poul Nissen, Thomas Boesen, Jesper Lykkegaard Karlsen, Bjørn Panyella Pedersen
Published 2019-07-01

Large scale identification and categorization of protein sequences using structured logistic regression.

by Bjørn P Pedersen, Georgiana Ifrim, Poul Liboriussen, Kristian B Axelsen, Michael G Palmgren, Poul Nissen, Carsten Wiuf, Christian N S Pedersen
Published 2014-01-01

Crystal Structure of an Ammonia-Permeable Aquaporin.

by Andreas Kirscht, Shreyas S Kaptan, Gerd Patrick Bienert, François Chaumont, Poul Nissen, Bert L de Groot, Per Kjellbom, Pontus Gourdon, Urban Johanson
Published 2016-03-01

A conserved leucine occupies the empty substrate site of LeuT in the Na+-free return state

by Lina Malinauskaite, Saida Said, Caglanur Sahin, Julie Grouleff, Azadeh Shahsavar, Henriette Bjerregaard, Pernille Noer, Kasper Severinsen, Thomas Boesen, Birgit Schiøtt, Steffen Sinning, Poul Nissen
Published 2016-05-01

Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease...

by Elinor Lazarov, Merle Hillebrand, Simone Schröder, Katharina Ternka, Julia Hofhuis, Andreas Ohlenbusch, Alonso Barrantes-Freer, Luis A. Pardo, Marlene U. Fruergaard, Poul Nissen, Knut Brockmann, Jutta Gärtner, Hendrik Rosewich
Published 2020-09-01

Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases

by Jacob Lauwring Andersen, Borbala Gesser, Erik Daa Funder, Christine Juul Fælled Nielsen, Helle Gotfred-Rasmussen, Mads Kirchheiner Rasmussen, Rachel Toth, Kurt Vesterager Gothelf, J. Simon C. Arthur, Lars Iversen, Poul Nissen
Published 2018-10-01

Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs

by Muwan Chen, Muwan Chen, Sofie H. Laursen, Sofie H. Laursen, Mette Habekost, Mette Habekost, Camilla H. Knudsen, Camilla H. Knudsen, Susanne H. Buchholdt, Susanne H. Buchholdt, Jinrong Huang, Jinrong Huang, Fengping Xu, Fengping Xu, Fengping Xu, Fengping Xu, Xin Liu, Xin Liu, Lars Bolund, Lars Bolund, Lars Bolund, Lars Bolund, Yonglun Luo, Yonglun Luo, Yonglun Luo, Yonglun Luo, Poul Nissen, Poul Nissen, Fabia Febbraro, Fabia Febbraro, Mark Denham, Mark Denham
Published 2018-02-01

A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.

by Hassina Azouaoui, Cédric Montigny, Miriam-Rose Ash, Frank Fijalkowski, Aurore Jacquot, Christina Grønberg, Rosa L López-Marqués, Michael G Palmgren, Manuel Garrigos, Marc le Maire, Paulette Decottignies, Pontus Gourdon, Poul Nissen, Philippe Champeil, Guillaume Lenoir
Published 2014-01-01

X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

by Kamil Gotfryd, Thomas Boesen, Jonas S. Mortensen, George Khelashvili, Matthias Quick, Daniel S. Terry, Julie W. Missel, Michael V. LeVine, Pontus Gourdon, Scott C. Blanchard, Jonathan A. Javitch, Harel Weinstein, Claus J. Loland, Poul Nissen, Ulrik Gether
Published 2020-02-01

Structural studies of P-type ATPase–ligand complexes using an X-ray free-electron laser

by Maike Bublitz, Karol Nass, Nikolaj D. Drachmann, Anders J. Markvardsen, Matthias J. Gutmann, Thomas R. M. Barends, Daniel Mattle, Robert L. Shoeman, R. Bruce Doak, Sébastien Boutet, Marc Messerschmidt, Marvin M. Seibert, Garth J. Williams, Lutz Foucar, Linda Reinhard, Oleg Sitsel, Jonas L. Gregersen, Johannes D. Clausen, Thomas Boesen, Kamil Gotfryd, Kai-Tuo Wang, Claus Olesen, Jesper V. Møller, Poul Nissen, Ilme Schlichting
Published 2015-07-01