Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.

by Poorva Sandlesh, Thierry Juang, Alfiya Safina, Michael J Higgins, Katerina V Gurova
Published 2018-01-01

Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation

by Poorva Sandlesh, Alfiya Safina, Imon Goswami, Laura Prendergast, Spenser Rosario, Eduardo C. Gomez, Jianmin Wang, Katerina V. Gurova
Published 2020-06-01

TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells

by Katerina Leonova, Alfiya Safina, Elimelech Nesher, Poorva Sandlesh, Rachel Pratt, Catherine Burkhart, Brittany Lipchick, Ilya Gitlin, Costakis Frangou, Igor Koman, Jianmin Wang, Kirill Kirsanov, Marianna G Yakubovskaya, Andrei V Gudkov, Katerina Gurova
Published 2018-02-01

Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution

by Jacob R. Leistico, Priyanka Saini, Christopher R. Futtner, Miroslav Hejna, Yasuhiro Omura, Pritin N. Soni, Poorva Sandlesh, Magdy Milad, Jian-Jun Wei, Serdar Bulun, J. Brandon Parker, Grant D. Barish, Jun S. Song, Debabrata Chakravarti
Published 2021-03-01

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

by Itay Raphael, Rajeev Kumar, Lauren H. McCarl, Karsen Shoger, Lin Wang, Poorva Sandlesh, Chaim T. Sneiderman, Jordan Allen, Shuyan Zhai, Marissa Lynn Campagna, Alexandra Foster, Tullia C. Bruno, Sameer Agnihotri, Baoli Hu, Brandyn A. Castro, Frank S. Lieberman, Alberto Broniscer, Aaron A. Diaz, Nduka M. Amankulor, Dhivyaa Rajasundaram, Ian F. Pollack, Gary Kohanbash, Gary Kohanbash
Published 2021-05-01