Therapeutic genome editing: prospects and challenges

by Cox, David Benjamin Turitz, Platt, Randall Jeffrey, Zhang, Feng
Published 2016

Efficient CRISPR/Cas9-mediated genome editing in P. falciparum

by Zhang, Feng, Wagner, Jeffrey C., Platt, Randall Jeffrey, Goldfless, Stephen J., Niles, Jacquin
Published 2015

Optogenetic skeletal muscle-powered adaptive biological machines

by Raman, Ritu, Cvetkovic, Caroline, Sengupta, Parijat, Bashir, Rashid, Uzel, Sebastien GM, Platt, Randall Jeffrey, Kamm, Roger Dale
Published 2016

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

by Joung, Julia, Konermann, Silvana M, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Platt, Randall Jeffrey, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng
Published 2017

Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation

by Gao, Xiaofei, Lee, Hsiang-Ying, Li, Wenbo, Barrasa, M. Inmaculada, Ma, Qi, Elmes, Russell R., Rosenfeld, Michael G., Platt, Randall Jeffrey, Lodish, Harvey F
Published 2018

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening

by Wang, Guangchuan, Chow, Ryan D., Ye, Lupeng, Guzman, Christopher D., Dai, Xiaoyun, Dong, Matthew B., Zhang, Feng, Platt, Randall Jeffrey, Chen, Sidi, Sharp, Phillip A.
Published 2018

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

by Platt, Randall Jeffrey, Subramanian, Vidya, Pearl, Taylor M., Rowlands, Christopher, Chan, Vincent, Boyer, Laurie Ann, So, Peter T. C., Kamm, Roger Dale, Uzel, Sebastien Guy Marcel
Published 2017

Optical control of mammalian endogenous transcription and epigenetic states

by Church, George M., Konermann, Silvana M, Brigham, Mark D, Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Zhang, Feng
Published 2017

Optical control of mammalian endogenous transcription and epigenetic states

by Konermann, Silvana M., Brigham, Mark D., Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Church, George M., Zhang, Feng
Published 2016

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits

by Shetty, Ashwin S., Weisbach, Niels R., Crabtree, Gerald R., Platt, Randall Jeffrey, Zhou, Yang, Slaymaker, Ian, Kim, Jinah, Sharma, Jitendra, Desai, Mitul, Sood, Sabina, Kempton, Hannah R., Feng, Guoping, Zhang, Feng
Published 2017

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

by Chow, Ryan D, Guzman, Christopher D, Wang, Guangchuan, Schmidt, Florian, Youngblood, Mark W, Ye, Lupeng, Errami, Youssef, Dong, Matthew B, Martinez, Michael A, Zhang, Sensen, Renauer, Paul, Bilguvar, Kaya, Gunel, Murat, Zhang, Feng, Platt, Randall J, Chen, Sidi, Sharp, Phillip A.
Published 2018

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

by Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M, Herbst, Rebecca H, Ye, Chun Jimmie, Przybylski, Dariusz, Tirosh, Itay, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A, Hacohen, Nir, Regev, Aviv, Dixit, Atray C., Platt, Randall Jeffrey, Sanjana, Neville E, Shalem, Ophir, Zhang, Feng
Published 2017

Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features

by Madison, Jon M, Duong, Karen, Vieux, Ellen F, Udeshi, Namrata D, Iqbal, Sumaiya, Requadt, Elise, Fereshetian, Shaunt, Lewis, Michael C, Gomes, Antonio S, Pierce, Kerry A, Platt, Randall J, Zhang, Feng, Campbell, Arthur J, Lal, Dennis, Wagner, Florence F, Clish, Clary B, Carr, Steven A, Sheng, Morgan, Scolnick, Edward M, Cottrell, Jeffrey R
Published 2021

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

by Chen, Sidi, Zhou, Yang, Yim, Michael J, Swiech, Lukasz, Kempton, Hannah R, Dahlman, James E, Parnas, Oren, Eisenhaure, Thomas M, Jovanovic, Marko, Graham, Daniel B, Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J, Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng, Anderson, Daniel Griffith, Kempton, Hannah R., Dahlman, James E., Sharp, Phillip A., Langer, Robert S, Platt, Randall Jeffrey, Yim, Michael
Published 2016