Semi-Mechanistic Modeling of Florfenicol Time-Kill Curves and in silico Dose Fractionation for Calf Respiratory Pathogens

by Ludovic Pelligand, Peter Lees, Pritam Kaur Sidhu, Pierre-Louis Toutain, Pierre-Louis Toutain
Published 2019-06-01

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients

by Alain Bousquet-Mélou, Anne Lespine, Jean-François Sutra, Isabelle Bargues, Pierre-Louis Toutain, Pierre-Louis Toutain
Published 2021-05-01

Implementing Precision Antimicrobial Therapy for the Treatment of Bovine Respiratory Disease: Current Limitations and Perspectives

by Guillaume Lhermie, Pierre-Louis Toutain, Pierre-Louis Toutain, Farid El Garch, Alain Bousquet-Mélou, Alain Bousquet-Mélou, Sébastien Assié
Published 2017-08-01

VetCAST Method for Determination of the Pharmacokinetic-Pharmacodynamic Cut-Off Values of a Long-Acting Formulation of Florfenicol to Support Clinical Breakpoints for Florfenicol A...

by Pierre-Louis Toutain, Pierre-Louis Toutain, Pritam Kaur Sidhu, Pritam Kaur Sidhu, Peter Lees, Ali Rassouli, Ali Rassouli, Ludovic Pelligand
Published 2019-06-01

En Route towards European Clinical Breakpoints for Veterinary Antimicrobial Susceptibility Testing: A Position Paper Explaining the VetCAST Approach

by Pierre-Louis Toutain, Pierre-Louis Toutain, Alain Bousquet-Mélou, Peter Damborg, Aude A. Ferran, Dik Mevius, Ludovic Pelligand, Kees T. Veldman, Peter Lees
Published 2017-12-01

Comparison of the in vitro activity of five antimicrobial drugs on Staphylococcus pseudintermedius and Staphylococcus aureus biofilms

by Aude A Ferran, JingJing LIU, Alain Bousquet-Mélou, Pierre-Louis TOUTAIN
Published 2016-08-01

Veterinary Medicine Needs New Green Antimicrobial Drugs

by Pierre-Louis TOUTAIN, Aude A Ferran, Alain Bousquet-Mélou, Ludovic Pelligand, Peter LEES
Published 2016-08-01

Bacterial Species-Specific Activity of a Fluoroquinolone against Two Closely Related Pasteurellaceae with Similar MICs: Differential In Vitro Inoculum Effects and In Vivo Efficacie...

by Guillaume Lhermie, Farid El Garch, Pierre-Louis Toutain, Aude A Ferran, Alain Bousquet-Mélou
Published 2015-01-01

Infection-stage adjusted dose of beta-lactams for parsimonious and efficient antibiotic treatments: A Pasteurella multocida experimental pneumonia in mice.

by Maleck V Vasseur, Marlene Z Lacroix, Pierre-Louis Toutain, Alain Bousquet-Melou, Aude A Ferran
Published 2017-01-01

Population Pharmacokinetic Study of Cefazolin Used Prophylactically in Canine Surgery for Susceptibility Testing Breakpoint Determination

by Petra Cagnardi, Federica Di Cesare, Pierre-Louis Toutain, Alain Bousquet-Mélou, Giuliano Ravasio, Roberto Villa
Published 2018-10-01

Dynamic interactions between cephalexin and macrophages on different Staphylococcus aureus inoculum sizes: a tripartite in vitro model

by Elodie Anne Lallemand, Claudine Zemirline, Pierre-Louis Toutain, Alain Bousquet-Melou, Aude A. Ferran, Séverine Boullier
Published 2021-01-01

Evaluating a tylosin dosage regimen for treatment of Staphylococcus delphini infection in mink (Neovison vison): a pharmacokinetic-pharmacodynamic approach

by Amir Atabak Ronaghinia, Julie Melsted Birch, Henrik Lauritz Frandsen, Pierre-Louis Toutain, Peter Damborg, Tina Struve
Published 2021-02-01

Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus.

by Diane C Broussou, Pierre-Louis Toutain, Frédérique Woehrlé, Farid El Garch, Alain Bousquet-Melou, Aude A Ferran
Published 2019-01-01

Bisphenol S instead of Bisphenol A: Toxicokinetic investigations in the ovine materno-feto-placental unit

by Flore C. Grandin, Marlène Z. Lacroix, Véronique Gayrard, Glenn Gauderat, Hanna Mila, Pierre-Louis Toutain, Nicole Picard-Hagen
Published 2018-11-01

Toxicokinetics of bisphenol-S and its glucuronide in plasma and urine following oral and dermal exposure in volunteers for the interpretation of biomonitoring data

by Imèn Khmiri, Jonathan Côté, Marc Mantha, Rania Khemiri, Marlène Lacroix, Clémence Gely, Pierre-Louis Toutain, Nicole Picard-Hagen, Véronique Gayrard, Michèle Bouchard
Published 2020-05-01

Differential Activity of the Combination of Vancomycin and Amikacin on Planktonic vs. Biofilm-Growing Staphylococcus aureus Bacteria in a Hollow Fiber Infection Model

by Diane C. Broussou, Diane C. Broussou, Marlène Z. Lacroix, Pierre-Louis Toutain, Frédérique Woehrlé, Farid El Garch, Alain Bousquet-Melou, Aude A. Ferran
Published 2018-03-01

Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A (BPA).

by Annette M Hormann, Frederick S Vom Saal, Susan C Nagel, Richard W Stahlhut, Carol L Moyer, Mark R Ellersieck, Wade V Welshons, Pierre-Louis Toutain, Julia A Taylor
Published 2014-01-01

Towards a Better and Harmonized Education in Antimicrobial Stewardship in European Veterinary Curricula

by Carmen Espinosa-Gongora, Lisbeth Rem Jessen, Oliver James Dyar, Alain Bousquet-Melou, Bruno González-Zorn, Céline Pulcini, Giovanni Re, Stefan Schwarz, Dorina Timofte, Pierre-Louis Toutain, Luca Guardabassi, The PREPARE-VET Working Group on behalf of ESCMID Study Groups for Veterinary Microbiology (ESGVM) and for Antimicrobial Stewardship (ESGVM)
Published 2021-03-01