Antibodies in falciparum malaria: what matters most, quantity or quality?

by Hasnaa Bouharoun-Tayoun, Pierre Druilhe
Published 1992-01-01

Immune mechanisms underlying the premunition against Plasmodium falciparum malaria

by Jean Louis Pérignon, Pierre Druilhe
Published 1994-01-01

Pre-clinical assessment of novel multivalent MSP3 malaria vaccine constructs.

by Gilles Bang, Eric Prieur, Christian Roussilhon, Pierre Druilhe
Published 2011-01-01

Mechanisms of immune protection in the asexual blood stage infection by Plasmodium falciparum: analysis by in vitro and ex-vivo assays

by Jurg Gysin, Pierre Druilhe, Luiz Pereira da Silva
Published 1992-01-01

Understanding human-Plasmodium falciparum immune interactions uncovers the immunological role of worms.

by Christian Roussilhon, Philippe Brasseur, Patrice Agnamey, Jean-Louis Pérignon, Pierre Druilhe
Published 2010-01-01

A conserved multi-gene family induces cross-reactive antibodies effective in defense against Plasmodium falciparum.

by Subhash Singh, Soe Soe, Simon Weisman, John W Barnwell, Jean Louis Pérignon, Pierre Druilhe
Published 2009-01-01

Further improvements of the P. falciparum humanized mouse model.

by Ludovic Arnold, Rajeev Kumar Tyagi, Pedro Meija, Claire Swetman, James Gleeson, Jean-Louis Pérignon, Pierre Druilhe
Published 2011-01-01

A novel merozoite surface antigen of Plasmodium falciparum (MSP-3) identified by cellular-antibody cooperative mechanism antigenicity and biological activity of antibodies

by Claude Oeuvray, Hasnaa Bouharoun-Tayoun, Heléne Grass-Masse, Jean Paul Iepers, Laurence Ralamboranto, André Tartar, Pierre Druilhe
Published 1994-01-01

Evaluating Human Immune Responses for Vaccine Development in a Novel Human Spleen Cell-Engrafted NOD-SCID-IL2rγNull Mouse Model

by Stéphanie Ghosn, Stéphanie Ghosn, Soulaima Chamat, Soulaima Chamat, Eric Prieur, Antoine Stephan, Pierre Druilhe, Hasnaa Bouharoun-Tayoun
Published 2018-03-01

A distinct peripheral blood monocyte phenotype is associated with parasite inhibitory activity in acute uncomplicated Plasmodium falciparum malaria.

by Pattamawan Chimma, Christian Roussilhon, Panudda Sratongno, Ronnatrai Ruangveerayuth, Kovit Pattanapanyasat, Jean-Louis Pérignon, David J Roberts, Pierre Druilhe
Published 2009-10-01

A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum.

by Pierre Druilhe, François Spertini, Daw Soesoe, Giampietro Corradin, Pedro Mejia, Subhash Singh, Regine Audran, Ahmed Bouzidi, Claude Oeuvray, Christian Roussilhon
Published 2005-11-01

High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

by Rajeev K. Tyagi, Patrick J. Gleeson, Ludovic Arnold, Rachida Tahar, Eric Prieur, Laurent Decosterd, Jean-Louis Pérignon, Piero Olliaro, Pierre Druilhe
Published 2018-10-01

Long-term clinical protection from falciparum malaria is strongly associated with IgG3 antibodies to merozoite surface protein 3.

by Christian Roussilhon, Claude Oeuvray, Christine Müller-Graf, Adama Tall, Christophe Rogier, Jean-François Trape, Michael Theisen, Aissatou Balde, Jean-Louis Pérignon, Pierre Druilhe
Published 2007-11-01

Genetic immunisation by liver stage antigen 3 protects chimpanzees against malaria despite low immune responses.

by Pierre Daubersies, Benjamin Ollomo, Jean-Pierre Sauzet, Karima Brahimi, Blanca-Liliana Perlaza, Wijnand Eling, Hubert Moukana, Pierre Rouquet, Charles de Taisne, Pierre Druilhe
Published 2008-01-01

PCR characterization of isolates from various endemic areas: diversity and turn over of Plasmodium falciparum populations are correlated with transmission

by Pierre Daubersies, Selma Sallenave-Sales, Jean Francois Trape, Lucie Raharimalala, Christophe Rogier, Hughes Contamin, Thierry Fandeur, Claudio T. Daniel-Ribeiro, Odile Mercereau-Puijalon, Pierre Druilhe
Published 1994-01-01

Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences.

by Masanori Yagi, Gilles Bang, Takahiro Tougan, Nirianne M Q Palacpac, Nobuko Arisue, Taiki Aoshi, Yoshitsugu Matsumoto, Ken J Ishii, Thomas G Egwang, Pierre Druilhe, Toshihiro Horii
Published 2014-01-01

Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.

by Viviane Villard, George W Agak, Géraldine Frank, Ali Jafarshad, Catherine Servis, Issa Nébié, Sodiomon B Sirima, Ingrid Felger, Myriam Arevalo-Herrera, Socrates Herrera, Frederic Heitz, Volker Bäcker, Pierre Druilhe, Andrey V Kajava, Giampietro Corradin
Published 2007-07-01

Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes

by Janaiara A. Cunha, Leonardo J. M. Carvalho, Cesare Bianco-Junior, Márcia C. R. Andrade, Lilian R. Pratt-Riccio, Evelyn K. P. Riccio, Marcelo Pelajo-Machado, Igor J. da Silva, Pierre Druilhe, Cláudio Tadeu Daniel-Ribeiro
Published 2017-09-01

A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide® ISA 720.

by James S McCarthy, Joanne Marjason, Suzanne Elliott, Paul Fahey, Gilles Bang, Elissa Malkin, Eveline Tierney, Hayley Aked-Hurditch, Christopher Adda, Nadia Cross, Jack S Richards, Freya J I Fowkes, Michelle J Boyle, Carole Long, Pierre Druilhe, James G Beeson, Robin F Anders
Published 2011-01-01

Correction: Safety and Immunogenicity of the Malaria Vaccine Candidate MSP3 Long Synthetic Peptide in 12–24 Months-Old Burkinabe Children

by Sodiomon B. Sirima, Alfred B. Tiono, Alphonse Ouédraogo, Amidou Diarra, André Lin Ouédraogo, Jean Baptiste Yaro, Espérance Ouédraogo, Adama Gansané, Edith C. Bougouma, Amadou T. Konaté, Youssouf Kaboré, Abdoulaye Traoré, Chilengi Roma, Issiaka Soulama, Adrian J. F. Luty, Pierre Druilhe, Simon Cousens, Issa Nébié
Published 2010-01-01