CREB-dependent LPA-induced signaling initiates a pro-fibrotic feedback loop between small airway basal cells and fibroblasts

by Shyam Nathan, Haijun Zhang, Mirko Andreoli, Philip L. Leopold, Ronald G. Crystal
Published 2021-04-01

Smoking is associated with shortened airway cilia.

by Philip L Leopold, Michael J O'Mahony, X Julie Lian, Ann E Tilley, Ben-Gary Harvey, Ronald G Crystal
Published 2009-12-01

Role of KRAS in regulating normal human airway basal cell differentiation

by Fumihiro Ogawa, Matthew S. Walters, Afrah Shafquat, Sarah L. O’Beirne, Robert J. Kaner, Jason G. Mezey, Haijun Zhang, Philip L. Leopold, Ronald G. Crystal
Published 2019-08-01

Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity

by Guoqing Wang, Howard H. Lou, Jacqueline Salit, Philip L. Leopold, Sharon Driscoll, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
Published 2019-08-01

Smoking shifts human small airway epithelium club cells toward a lesser differentiated population

by Mahboubeh R. Rostami, Michelle G. LeBlanc, Yael Strulovici-Barel, Wulin Zuo, Jason G. Mezey, Sarah L. O’Beirne, Robert J. Kaner, Philip L. Leopold, Ronald G. Crystal
Published 2021-09-01

Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids

by Philip L. Leopold, Vassilia Partali, Hans-Richard Sliwka, Rachel Jones, Liji Raju, Nada Abdul Khalique, Tarek Ibrahim, Nour Barakat, Mais Al-Kawaz, Christer L. Øpstad, Michael D. Pungente, Emile Jubeli
Published 2012-03-01

Dysregulation of club cell biology in idiopathic pulmonary fibrosis.

by Wu-Lin Zuo, Mahboubeh R Rostami, Michelle LeBlanc, Robert J Kaner, Sarah L O'Beirne, Jason G Mezey, Philip L Leopold, Karsten Quast, Sudha Visvanathan, Jay S Fine, Matthew J Thomas, Ronald G Crystal
Published 2020-01-01

Dysregulation of club cell biology in idiopathic pulmonary fibrosis

by Wu-Lin Zuo, Mahboubeh R. Rostami, Michelle LeBlanc, Robert J. Kaner, Sarah L. O’Beirne, Jason G. Mezey, Philip L. Leopold, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal, Y. Peter Di
Published 2020-01-01

Cell-specific expression of lung disease risk-related genes in the human small airway epithelium

by Wu-lin Zuo, Mahboubeh R. Rostami, Shushila A. Shenoy, Michelle G. LeBlanc, Jacqueline Salit, Yael Strulovici-Barel, Sarah L. O’Beirne, Robert J. Kaner, Philip L. Leopold, Jason G. Mezey, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
Published 2020-07-01