The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer

by Raheleh Amirkhah, Hojjat Naderi-Meshkin, Jaynish S. Shah, Philip D. Dunne, Ulf Schmitz
Published 2019-08-01

Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data.

by Darragh G McArt, Philip D Dunne, Jaine K Blayney, Manuel Salto-Tellez, Sandra Van Schaeybroeck, Peter W Hamilton, Shu-Dong Zhang
Published 2013-01-01

Downregulation of PPARα during Experimental Left Ventricular Hypertrophy Is Critically Dependent on Nox2 NADPH Oxidase Signalling

by Adam P. Harvey, Emma Robinson, Kevin S. Edgar, Ross McMullan, Karla M. O’Neill, Matthew Alderdice, Raheleh Amirkhah, Philip D. Dunne, Barbara J. McDermott, David J. Grieve
Published 2020-06-01

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

by Philip D. Dunne, Matthew Alderdice, Paul G. O'Reilly, Aideen C. Roddy, Amy M. B. McCorry, Susan Richman, Tim Maughan, Simon S. McDade, Patrick G. Johnston, Daniel B. Longley, Elaine Kay, Darragh G. McArt, Mark Lawler
Published 2017-05-01

ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer

by Sandra Van Schaeybroeck, Murugan Kalimutho, Philip D. Dunne, Robbie Carson, Wendy Allen, Puthen V. Jithesh, Keara L. Redmond, Takehiko Sasazuki, Senji Shirasawa, Jaine Blayney, Paolo Michieli, Cathy Fenning, Heinz-Josef Lenz, Mark Lawler, Daniel B. Longley, Patrick G. Johnston
Published 2014-06-01