Alleles Alzheimer Disease Alzheimer disease Alzheimer’s disease Apolipoprotein E Apolipoproteins E Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans LSR Polymorphism, Single Nucleotide VEGF-A Vascular Endothelial Growth Factor A allele apolipoprotein E elastic net epistasis genetic predisposition genetics genome-wide association study genotype human machine learning metabolism prediction single nucleotide polymorphism vasculotropin A