Adult Article Cancer predisposition DNA Copy Number Variations DNA Repair DNA repair Early-onset cancer Fanconi anemia group G protein Genetic Predisposition to Disease Germ Cells Germ-Line Mutation Head and Neck Neoplasms Humans Middle Aged Oral cavity carcinomas Oropharynx carcinomas Risk factors Squamous Cell Carcinoma of Head and Neck Whole-exome sequencing adult cancer risk cancer susceptibility clinical article copy number variation cyclin dependent kinase inhibitor 2A female genetic predisposition genetic variability genetics germ cell