Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture.

by Julia Caldwell, Weijia Wang, Peter W Zandstra
Published 2015-01-01

Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?

by Serena Tedesco, Federica De Majo, Jieun Kim, Annalisa Trenti, Lucia Trevisi, Gian Paolo Fadini, Gian Paolo Fadini, Chiara Bolego, Peter W. Zandstra, Peter W. Zandstra, Peter W. Zandstra, Andrea Cignarella, Libero Vitiello, Libero Vitiello
Published 2018-02-01

Local BMP-SMAD1 Signaling Increases LIF Receptor-Dependent STAT3 Responsiveness and Primed-to-Naive Mouse Pluripotent Stem Cell Conversion Frequency

by Kento Onishi, Peter D. Tonge, Andras Nagy, Peter W. Zandstra
Published 2014-07-01

Context-explorer: Analysis of spatially organized protein expression in high-throughput screens.

by Joel Ostblom, Emanuel J P Nazareth, Mukul Tewary, Peter W Zandstra
Published 2019-01-01

Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens.

by Raheem Peerani, Kento Onishi, Alborz Mahdavi, Eugenia Kumacheva, Peter W Zandstra
Published 2009-07-01

Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates.

by Mark D Ungrin, Chirag Joshi, Andra Nica, Céline Bauwens, Peter W Zandstra
Published 2008-02-01

Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.

by Alborz Mahdavi, Ryan E Davey, Patrick Bhola, Ting Yin, Peter W Zandstra
Published 2007-07-01

PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions.

by Wenlian Qiao, Gerald Quon, Elizabeth Csaszar, Mei Yu, Quaid Morris, Peter W Zandstra
Published 2012-01-01

Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence

by Nafees Rahman, Patrick M. Brauer, Lilian Ho, Tatiana Usenko, Mukul Tewary, Juan Carlos Zúñiga-Pflücker, Peter W. Zandstra
Published 2017-05-01

Microdroplet-based one-step RT-PCR for ultrahigh throughput single-cell multiplex gene expression analysis and rare cell detection

by Jennifer Ma, Gary Tran, Alwin M. D. Wan, Edmond W. K. Young, Eugenia Kumacheva, Norman N. Iscove, Peter W. Zandstra
Published 2021-03-01

Oct4 is required ~E7.5 for proliferation in the primitive streak.

by Brian DeVeale, Irina Brokhman, Paria Mohseni, Tomas Babak, Charles Yoon, Anthony Lin, Kento Onishi, Alexey Tomilin, Larysa Pevny, Peter W Zandstra, Andras Nagy, Derek van der Kooy
Published 2013-11-01

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

by Dominika Dziedzicka, Mukul Tewary, Alexander Keller, Laurentijn Tilleman, Laura Prochazka, Joel Östblom, Edouard Couvreu De Deckersberg, Christina Markouli, Silvie Franck, Filip Van Nieuwerburgh, Claudia Spits, Peter W. Zandstra, Karen Sermon, Mieke Geens
Published 2021-03-01

FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors

by Charles Yoon, Hannah Song, Ting Yin, Damaris Bausch-Fluck, Andreas P. Frei, Steven Kattman, Nicole Dubois, Alec D. Witty, Johannes A. Hewel, Hongbo Guo, Andrew Emili, Bernd Wollscheid, Gordon Keller, Peter W. Zandstra
Published 2018-01-01

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning.

by Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, Fiona M Watt, Peter W Zandstra
Published 2019-10-01

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

by Alessandra Vigilante, Anna Laddach, Nathalie Moens, Ruta Meleckyte, Andreas Leha, Arsham Ghahramani, Oliver J. Culley, Annie Kathuria, Chloe Hurling, Alice Vickers, Erika Wiseman, Mukul Tewary, Peter W. Zandstra, Richard Durbin, Franca Fraternali, Oliver Stegle, Ewan Birney, Nicholas M. Luscombe, Davide Danovi, Fiona M. Watt
Published 2019-02-01

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias

by Rocco Romagnuolo, Hassan Masoudpour, Andreu Porta-Sánchez, Beiping Qiang, Jennifer Barry, Andrew Laskary, Xiuling Qi, Stéphane Massé, Karl Magtibay, Hiroyuki Kawajiri, Jun Wu, Tamilla Valdman Sadikov, Janet Rothberg, Krishna M. Panchalingam, Emily Titus, Ren-Ke Li, Peter W. Zandstra, Graham A. Wright, Kumaraswamy Nanthakumar, Nilesh R. Ghugre, Gordon Keller, Michael A. Laflamme
Published 2019-05-01