Mitochondrial Dysfunction and the Aging Immune System

by Peter J. McGuire
Published 2019-05-01

A new mouse model of mild ornithine transcarbamylase deficiency (spf-j) displays cerebral amino acid perturbations at baseline and upon systemic immune activation.

by Tatyana N Tarasenko, Odrick R Rosas, Larry N Singh, Kara Kristaponis, Hilary Vernon, Peter J McGuire
Published 2015-01-01

Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency

by Peter J. McGuire, Tatiana N. Tarasenko, Tony Wang, Ezra Levy, Patricia M. Zerfas, Thomas Moran, Hye Seung Lee, Brian J. Bequette, George A. Diaz
Published 2014-02-01

Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity

by Maxim Jestin, Senta M. Kapnick, Tatyana N. Tarasenko, Cassidy T. Burke, Patricia M. Zerfas, Francisca Diaz, Hilary Vernon, Larry N. Singh, Ronald J. Sokol, Peter J. McGuire
Published 2020-07-01