The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Res...

by Peter H. Schafer, Peng Chen, Lorraine Fang, Andrew Wang, Rajesh Chopra
Published 2015-01-01

Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice

by Peter H. Schafer, Mary Adams, Gerald Horan, Francesca Truzzi, Alessandra Marconi, Carlo Pincelli
Published 2019-10-01

Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients.

by Anita K Gandhi, Tao Shi, Mingyu Li, Ulf Jungnelius, Alfredo Romano, Josep Tabernero, Salvatore Siena, Peter H Schafer, Rajesh Chopra
Published 2013-01-01

Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study

by Peter H. Schafer, Alan J. Kivitz, Jianglin Ma, Shimon Korish, Donna Sutherland, Li Li, Ada Azaryan, Jolanta Kosek, Mary Adams, Lori Capone, Eun Mi Hur, Douglas R. Hough, Garth E. Ringheim
Published 2019-11-01

Apremilast Ameliorates Experimental Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of CD4+Foxp3+ Regulatory T Cells Differentiation

by Weiqian Chen, Weiqian Chen, Julie Wang, Zhenjian Xu, Zhenjian Xu, Feng Huang, Wenbin Qian, Jilin Ma, Hwa bok Wee, Gregory S. Lewis, Rayford R. June, Peter H. Schafer, Jin Lin, Song Guo Zheng
Published 2018-07-01