Current and future therapeutic strategies for the treatment of retinal neurodegenerative diseases

by Victoria Maneu, Pedro Lax, Nicolás Cuenca
Published 2022-01-01

Photosensitive Melanopsin-Containing Retinal Ganglion Cells in Health and Disease: Implications for Circadian Rhythms

by Pedro Lax, Isabel Ortuño-Lizarán, Victoria Maneu, Manuel Vidal-Sanz, Nicolás Cuenca
Published 2019-06-01

Natural Compounds from Saffron and Bear Bile Prevent Vision Loss and Retinal Degeneration

by Laura Fernández-Sánchez, Pedro Lax, Agustina Noailles, Antonia Angulo, Victoria Maneu, Nicolás Cuenca
Published 2015-07-01

Safranal, a saffron constituent, attenuates retinal degeneration in P23H rats.

by Laura Fernández-Sánchez, Pedro Lax, Gema Esquiva, José Martín-Nieto, Isabel Pinilla, Nicolás Cuenca
Published 2012-01-01

Retinal Vascular Degeneration in the Transgenic P23H Rat Model of Retinitis Pigmentosa

by Laura Fernández-Sánchez, Gema Esquiva, Isabel Pinilla, Isabel Pinilla, Pedro Lax, Nicolás Cuenca, Nicolás Cuenca
Published 2018-06-01

Retinitis pigmentosa is associated with shifts in the gut microbiome

by Oksana Kutsyr, Lucía Maestre-Carballa, Mónica Lluesma-Gomez, Manuel Martinez-Garcia, Nicolás Cuenca, Pedro Lax
Published 2021-03-01

Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina

by Julián Esteve-Rudd, Laura Fernández-Sánchez, Pedro Lax, Emilio De Juan, José Martín-Nieto, Nicolás Cuenca
Published 2011-10-01

Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease

by Isabel Ortuño-Lizarán, Gema Esquiva, Thomas G. Beach, Geidy E. Serrano, Charles H. Adler, Pedro Lax, Nicolás Cuenca
Published 2018-09-01

Neuroprotective Effect of Tauroursodeoxycholic Acid on N-Methyl-D-Aspartate-Induced Retinal Ganglion Cell Degeneration.

by Violeta Gómez-Vicente, Pedro Lax, Laura Fernández-Sánchez, Netxibeth Rondón, Gema Esquiva, Francisco Germain, Pedro de la Villa, Nicolás Cuenca
Published 2015-01-01

The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina

by Agustina Noailles, Oksana Kutsyr, Victoria Maneu, Isabel Ortuño-Lizarán, Laura Campello, Emilio de Juan, Violeta Gómez-Vicente, Nicolás Cuenca, Nicolás Cuenca, Pedro Lax
Published 2019-02-01

Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.

by Sarah L Roche, Alice C Wyse-Jackson, Violeta Gómez-Vicente, Pedro Lax, Ana M Ruiz-Lopez, Ashleigh M Byrne, Nicolás Cuenca, Thomas G Cotter
Published 2016-01-01

Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats.

by Laura Fernández-Sánchez, Irene Bravo-Osuna, Pedro Lax, Alicia Arranz-Romera, Victoria Maneu, Sergio Esteban-Pérez, Isabel Pinilla, María Del Mar Puebla-González, Rocío Herrero-Vanrell, Nicolás Cuenca
Published 2017-01-01

New Nrf2-Inducer Compound ITH12674 Slows the Progression of Retinitis Pigmentosa in the Mouse Model rd10

by Laura Campello, Oksana Kutsyr, Agustina Noailles, Patrycja Michalska, Laura Fernández-Sánchez, Natalia Martínez-Gil, Isabel Ortuño-Lizarán, Xavier Sánchez-Sáez, Emilio de Juan, Pedro Lax, Rafael León, Antonio G. García, Nicolás Cuenca, Victoria Maneu
Published 2020-02-01