Increasing the throughput of crystallization condition screens: Challenges and pitfalls of acoustic dispensing systems

by Robin Kryštůfek, Pavel Šácha
Published 2019-01-01

Impact of posttranslational modifications on atomistic structure of fibrinogen.

by Žofie Sovová, Jana Štikarová, Jiřina Kaufmanová, Pavel Májek, Jiří Suttnar, Pavel Šácha, Martin Malý, Jan E Dyr
Published 2020-01-01

The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels

by Petra Dzianová, Seiya Asai, Martina Chrudinová, Lucie Kosinová, Pavlo Potalitsyn, Pavel Šácha, Romana Hadravová, Irena Selicharová, Jan Kříž, Johan P. Turkenburg, Andrzej Marek Brzozowski, Jiří Jiráček, Lenka Žáková
Published 2020-10-01

Inhibitor–Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms

by Klára Pospíšilová, Tomáš Knedlík, Pavel Šácha, Libor Kostka, Jiří Schimer, Jiří Brynda, Vlastimil Král, Petr Cígler, Václav Navrátil, Tomáš Etrych, Vladimír Šubr, Michael Kugler, Milan Fábry, Pavlína Řezáčová, Jan Konvalinka
Published 2019-04-01

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.

by Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubrt, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Published 2019-09-01

Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.

by Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubr, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Published 2019-10-01