miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

by Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay
Published 2018-12-01

A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice

by Hak Kyun Kim, Jianpeng Xu, Kirk Chu, Hyesuk Park, Hagoon Jang, Pan Li, Paul N. Valdmanis, Qiangfeng Cliff Zhang, Mark A. Kay
Published 2019-12-01

Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer’s disease

by Giulia Monti, Mads Kjolby, Anne Mette G. Jensen, Mariet Allen, Juliane Reiche, Peter L. Møller, Raquel Comaposada-Baró, Bartlomiej E. Zolkowski, Cármen Vieira, Margarita Melnikova Jørgensen, Ida E. Holm, Paul N. Valdmanis, Niels Wellner, Christian B. Vægter, Sarah J. Lincoln, Anders Nykjær, Nilüfer Ertekin-Taner, Jessica E. Young, Mette Nyegaard, Olav M. Andersen
Published 2021-03-01

Human Induced Pluripotent Stem Cell-Derived TDP-43 Mutant Neurons Exhibit Consistent Functional Phenotypes Across Multiple Gene Edited Lines Despite Transcriptomic and Splicing Dis...

by Alec S. T. Smith, Alec S. T. Smith, Changho Chun, Jennifer Hesson, Jennifer Hesson, Julie Mathieu, Julie Mathieu, Paul N. Valdmanis, David L. Mack, David L. Mack, David L. Mack, David L. Mack, Byung-Ok Choi, Byung-Ok Choi, Byung-Ok Choi, Deok-Ho Kim, Deok-Ho Kim, Deok-Ho Kim, Deok-Ho Kim, Mark Bothwell, Mark Bothwell
Published 2021-09-01