Prostate cancer stem cells: The case for model systems

by Paul G Hynes, Kathleen Kelly
Published 2012-01-01

Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.

by Wassim Abou-Kheir, Paul G Hynes, Philip Martin, Juan Juan Yin, Yen-Nien Liu, Victoria Seng, Ross Lake, Joshua Spurrier, Kathleen Kelly
Published 2011-01-01

TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation.

by Orla M Casey, Lei Fang, Paul G Hynes, Wassim G Abou-Kheir, Philip L Martin, Heather S Tillman, Gyorgy Petrovics, Hibah O Awwad, Yvona Ward, Ross Lake, Luhua Zhang, Kathleen Kelly
Published 2012-01-01

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

by Supreet Agarwal, Paul G. Hynes, Heather S. Tillman, Ross Lake, Wassim G. Abou-Kheir, Lei Fang, Orla M. Casey, Amir H. Ameri, Philip L. Martin, Juan Juan Yin, Phillip J. Iaquinta, Wouter R. Karthaus, Hans C. Clevers, Charles L. Sawyers, Kathleen Kelly
Published 2015-12-01