Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.

by Jennifer FitzGerald, Sylvie Moureau, Paul Drogaris, Enda O'Connell, Nebiyu Abshiru, Alain Verreault, Pierre Thibault, Muriel Grenon, Noel F Lowndes
Published 2011-02-01

H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation.

by Benoit Guillemette, Paul Drogaris, Hsiu-Hsu Sophia Lin, Harry Armstrong, Kyoko Hiragami-Hamada, Axel Imhof, Eric Bonneil, Pierre Thibault, Alain Verreault, Richard J Festenstein
Published 2011-03-01