In vitro growth competition experiments that suggest consequences of the substandard artemisinin epidemic that may be accelerating drug resistance in P. falciparum malaria.

by Matthew R Hassett, Paul D Roepe
Published 2021-01-01

Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance

by Laura E. Heller, Paul D. Roepe
Published 2019-06-01

Correction: Anti-Plasmodial Polyvalent Interactions in Artemisia annua L. Aqueous Extract – Possible Synergistic and Resistance Mechanisms

by John O. Suberu, Alexander P. Gorka, Lauren Jacobs, Paul D. Roepe, Neil Sullivan, Guy C. Barker, Alexei A. Lapkin
Published 2013-01-01

Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanisms.

by John O Suberu, Alexander P Gorka, Lauren Jacobs, Paul D Roepe, Neil Sullivan, Guy C Barker, Alexei A Lapkin
Published 2013-01-01

Correction: Anti-Plasmodial Polyvalent Interactions in L. Aqueous Extract – Possible Synergistic and Resistance Mechanisms.

by John O. Suberu, Alexander P. Gorka, Lauren Jacobs, Paul D. Roepe, Neil Sullivan, Guy C. Barker, Alexei A. Lapkin
Published 2013-01-01

A process similar to autophagy is associated with cytocidal chloroquine resistance in Plasmodium falciparum.

by David Gaviria, Michelle F Paguio, Lindsey B Turnbull, Asako Tan, Amila Siriwardana, Debasish Ghosh, Michael T Ferdig, Anthony P Sinai, Paul D Roepe
Published 2013-01-01

An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to fa...

by L Brock Thornton, Paige Teehan, Katherine Floyd, Christian Cochrane, Amy Bergmann, Bryce Riegel, Andrew J Stasic, Manlio Di Cristina, Silvia N J Moreno, Paul D Roepe, Zhicheng Dou
Published 2019-06-01

Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiol...

by Stanislaw J Gabryszewski, Satish K Dhingra, Jill M Combrinck, Ian A Lewis, Paul S Callaghan, Matthew R Hassett, Amila Siriwardana, Philipp P Henrich, Andrew H Lee, Nina F Gnädig, Lise Musset, Manuel Llinás, Timothy J Egan, Paul D Roepe, David A Fidock
Published 2016-11-01