The role of miR-29a in HIV-1 replication and latency

by Giacomo Frattari, Lars Aagaard, Paul W. Denton
Published 2017-10-01

Cryptopatches Are Essential for the Development of Human GALT

by Tomonori Nochi, Paul W. Denton, Angela Wahl, J. Victor Garcia
Published 2013-06-01

Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues

by Paul W. Denton, Ole S. Søgaard, Ole S. Søgaard, Martin Tolstrup, Martin Tolstrup
Published 2019-08-01

Poor compliance with an antibiotic directive—A call for intensified monitoring

by Frederik Novak, Jens T. Hørlück, Jacob D. Redder, Paul W. Denton, Merete Storgaard
Published 2021-03-01

Hypogammaglobulinemia in BLT humanized mice--an animal model of primary antibody deficiency.

by Francisco Martinez-Torres, Tomonori Nochi, Angela Wahl, J Victor Garcia, Paul W Denton
Published 2014-01-01

Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice.

by Morgan L Chateau, Paul W Denton, Michael D Swanson, Ian McGowan, J Victor Garcia
Published 2013-01-01

Immune checkpoints and the HIV-1 reservoir: proceed with caution

by Rikke Olesen, Steffen Leth, Rasmus Nymann, Lars Østergaard, Ole S. Søgaard, Paul W. Denton, Martin Tolstrup
Published 2016-07-01

Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice.

by Angela Wahl, Michael D Swanson, Tomonori Nochi, Rikke Olesen, Paul W Denton, Morgan Chateau, J Victor Garcia
Published 2012-01-01

Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency ex vivo without T cell activation

by Jesper D. Gunst, Kathrine Kjær, Rikke Olesen, Thomas A. Rasmussen, Lars Østergaard, Paul W. Denton, Ole S. Søgaard, Martin Tolstrup
Published 2019-07-01

Comparable human reconstitution following Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice.

by Anna Halling Folkmar Andersen, Stine Sofie Frank Nielsen, Rikke Olesen, Jakob Le Fèvre Harslund, Ole Schmeltz Søgaard, Lars Østergaard, Paul W Denton, Martin Tolstrup
Published 2020-01-01

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.

by Paul W Denton, Jacob D Estes, Zhifeng Sun, Florence A Othieno, Bangdong L Wei, Anja K Wege, Daniel A Powell, Deborah Payne, Ashley T Haase, J Victor Garcia
Published 2008-01-01

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice.

by Paul W Denton, John F Krisko, Daniel A Powell, Melissa Mathias, Youn Tae Kwak, Francisco Martinez-Torres, Wei Zou, Deborah A Payne, Jacob D Estes, J Victor Garcia
Published 2010-01-01

Administration of Panobinostat Is Associated with Increased IL-17A mRNA in the Intestinal Epithelium of HIV-1 Patients

by Ane Bjerg Christensen, Anders Dige, Johan Vad-Nielsen, Christel R. Brinkmann, Mia Bendix, Lars Østergaard, Martin Tolstrup, Ole S. Søgaard, Thomas A. Rasmussen, Jens Randel Nyengaard, Jørgen Agnholt, Paul W. Denton
Published 2015-01-01

Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-I...

by Christel Rothe Brinkmann, Jesper Falkesgaard Højen, Thomas Aagaard Rasmussen, Anne Sofie Kjær, Rikke Olesen, Paul W. Denton, Lars Østergaard, Zhengyu Ouyang, Mathias Lichterfeld, Xu Yu, Ole Schmeltz Søgaard, Charles Dinarello, Martin Tolstrup, Ana Fernandez-Sesma
Published 2018-02-01

Broad activation of latent HIV-1 in vivo

by Kirston Barton, Bonnie Hiener, Anni Winckelmann, Thomas Aagaard Rasmussen, Wei Shao, Karen Byth, Robert Lanfear, Ajantha Solomon, James McMahon, Sean Harrington, Maria Buzon, Mathias Lichterfeld, Paul W. Denton, Rikke Olesen, Lars Østergaard, Martin Tolstrup, Sharon R. Lewin, Ole Schmeltz Søgaard, Sarah Palmer
Published 2016-09-01

Targeted cytotoxic therapy kills persisting HIV infected cells during ART.

by Paul W Denton, Julie M Long, Stephen W Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D Snyder, Katherine Perkey, Nancie M Archin, Shailesh K Choudhary, Kuo Yang, Michael G Hudgens, Ira Pastan, Ashley T Haase, Angela D Kashuba, Edward A Berger, David M Margolis, J Victor Garcia
Published 2014-01-01

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

by Ole S Søgaard, Mette E Graversen, Steffen Leth, Rikke Olesen, Christel R Brinkmann, Sara K Nissen, Anne Sofie Kjaer, Mariane H Schleimann, Paul W Denton, William J Hey-Cunningham, Kersten K Koelsch, Giuseppe Pantaleo, Kim Krogsgaard, Maja Sommerfelt, Remi Fromentin, Nicolas Chomont, Thomas A Rasmussen, Lars Østergaard, Martin Tolstrup
Published 2015-09-01

TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodesResearch in context

by Mariane H. Schleimann, Maria-Louise Kobberø, Line K. Vibholm, Kathrine Kjær, Leila B. Giron, Kathleen Busman-Sahay, Chi Ngai Chan, Michael Nekorchuk, Manuel Schmidt, Burghardt Wittig, Tine E. Damsgaard, Peter Ahlburg, Michel B. Hellfritzsch, Kaja Zuwala, Frederik H. Rothemejer, Rikke Olesen, Phillipp Schommers, Florian Klein, Harsh Dweep, Andrew Kossenkov, Jens R. Nyengaard, Jacob D. Estes, Mohamed Abdel-Mohsen, Lars Østergaard, Martin Tolstrup, Ole S. Søgaard, Paul W. Denton
Published 2019-07-01