The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.

by Patricia Jaaks, Valentina D'Alessandro, Nicole Grob, Sina Büel, Katarina Hajdin, Beat W Schäfer, Michele Bernasconi
Published 2016-01-01

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

by Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A Merten, Mathew J Garnett, Julio Saez‐Rodriguez
Published 2020-06-01

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

by Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A Merten, Mathew J Garnett, Julio Saez‐Rodriguez
Published 2020-02-01

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

by Maria E. Gierisch, Gloria Pedot, Franziska Walser, Laura A. Lopez-Garcia, Patricia Jaaks, Felix K. Niggli, Beat W. Schäfer
Published 2019-01-01

Integrated cross-study datasets of genetic dependencies in cancer

by Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoc, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M. McFarland, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio
Published 2021-03-01

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

by Emanuel Gonçalves, Aldo Segura‐Cabrera, Clare Pacini, Gabriele Picco, Fiona M Behan, Patricia Jaaks, Elizabeth A Coker, Donny van derMeer, Andrew Barthorpe, Howard Lightfoot, Tatiana Mironenko, Alexandra Beck, Laura Richardson, Wanjuan Yang, Ermira Lleshi, James Hall, Charlotte Tolley, Caitlin Hall, Iman Mali, Frances Thomas, James Morris, Andrew R Leach, James T Lynch, Ben Sidders, Claire Crafter, Francesco Iorio, Stephen Fawell, Mathew J Garnett
Published 2020-07-01