The leukotriene B₄/BLT₁ axis is a key determinant in susceptibility and resistance to histoplasmosis.

by Adriana Secatto, Elyara Maria Soares, Gisele Aparecida Locachevic, Patricia Aparecida Assis, Francisco Wanderlei Garcia Paula-Silva, Carlos Henrique Serezani, Alexandra Ivo de Medeiros, Lúcia Helena Faccioli
Published 2014-01-01

GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands.

by Carlos Arterio Sorgi, Stephanie Rose, Nathalie Court, Daniela Carlos, Francisco Wanderley Garcia Paula-Silva, Patricia Aparecida Assis, Fabiani Gai Frantz, Bernhard Ryffel, Valerie Quesniaux, Lúcia Helena Faccioli
Published 2012-01-01