B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.

by Víctor González-Ruiz, Irene Pascua, Tamara Fernández-Marcelo, Pascual Ribelles, Giulia Bianchini, Vellaisamy Sridharan, Pilar Iniesta, M Teresa Ramos, Ana I Olives, M Antonia Martín, J Carlos Menéndez
Published 2014-01-01