Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

by Laura Piel, Laura Piel, Pascale Pescher, Gerald F. Späth
Published 2018-09-01

Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery.

by Jan Mani, Andreas Güttinger, Bernd Schimanski, Manfred Heller, Alvaro Acosta-Serrano, Pascale Pescher, Gerald Späth, Isabel Roditi
Published 2011-01-01

New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence.

by Guilherme D Melo, Sophie Goyard, Hervé Lecoeur, Eline Rouault, Pascale Pescher, Laurence Fiette, Alexandre Boissonnas, Paola Minoprio, Thierry Lang
Published 2017-09-01

Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

by Juvana Moreira Andrade, Leilane Oliveira Gonçalves, Daniel Barbosa Liarte, Davi Alvarenga Lima, Frederico Gonçalves Guimarães, Daniela de Melo Resende, Ana Maria Murta Santi, Luciana Marcia de Oliveira, João Paulo Linhares Velloso, Renato Guimarães Delfino, Pascale Pescher, Gerald F. Späth, Jeronimo Conceição Ruiz, Silvane Maria Fonseca Murta
Published 2020-11-01

Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

by Giovanni Bussotti, Evi Gouzelou, Mariana Côrtes Boité, Ihcen Kherachi, Zoubir Harrat, Naouel Eddaikra, Jeremy C. Mottram, Maria Antoniou, Vasiliki Christodoulou, Aymen Bali, Fatma Z. Guerfali, Dhafer Laouini, Maowia Mukhtar, Franck Dumetz, Jean-Claude Dujardin, Despina Smirlis, Pierre Lechat, Pascale Pescher, Adil El Hamouchi, Meryem Lemrani, Carmen Chicharro, Ivonne Pamela Llanes-Acevedo, Laura Botana, Israel Cruz, Javier Moreno, Fakhri Jeddi, Karim Aoun, Aïda Bouratbine, Elisa Cupolillo, Gerald F. Späth
Published 2018-11-01