How does the NPM1 mutant induce leukemia?

by Paolo Sportoletti
Published 2011-06-01

Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL

by Valerio Guarente, Paolo Sportoletti
Published 2021-03-01

Treatment of relapsed/refractory CLL with Venetoclax-Rituximab during the COVID-19 pandemic: A daily-life experience in southern Italy.

by Stefano Molica, Paolo Sportoletti, Nicola Di Renzo, Pellegrino Musto, Fabrizio Pane, Francesco Di Raimondo
Published 2021-06-01

A Curious Novel Combination of <i>Nucleophosmin</i> (<i>NPM1</i>) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of <i>NPM1</i> in Acute Myeloid Leukemia (AML)

by Alessandra Venanzi, Roberta Rossi, Giovanni Martino, Ombretta Annibali, Giuseppe Avvisati, Maria Grazia Mameli, Paolo Sportoletti, Enrico Tiacci, Brunangelo Falini, Maria Paola Martelli
Published 2021-09-01

Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia

by Valerio Guarente, Giovanni Martino, Erica Dorillo, Filomena De Falco, Chiara Rompietti, Daniele Sorcini, Mariangela Brogna, Valeria Cardinali, Stefano Ascani, Andrea Marra, Paolo Sportoletti
Published 2021-09-01

Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin

by Roberta La Starza, Tiziana Pierini, Lorenza Pastorino, Elisa Albi, Caterina Matteucci, Barbara Crescenzi, Paolo Sportoletti, Piero Covarelli, Franca Falzetti, Giovanni Roti, Stefano Ascani, Cristina Mecucci
Published 2018-01-01

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia

by Emanuela Rosati, Stefano Baldoni, Filomena De Falco, Beatrice Del Papa, Erica Dorillo, Chiara Rompietti, Elisa Albi, Franca Falzetti, Mauro Di Ianni, Mauro Di Ianni, Paolo Sportoletti
Published 2018-06-01

NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications

by Paolo Sportoletti, Filomena De Falco, Beatrice Del Papa, Stefano Baldoni, Valerio Guarente, Andrea Marra, Erica Dorillo, Chiara Rompietti, Francesco Maria Adamo, Loredana Ruggeri, Mauro Di Ianni, Emanuela Rosati
Published 2021-06-01

NOTCH and Graft-Versus-Host Disease

by Mauro Di Ianni, Mauro Di Ianni, Beatrice Del Papa, Stefano Baldoni, Ambra Di Tommaso, Bianca Fabi, Emanuela Rosati, Annalisa Natale, Stella Santarone, Paola Olioso, Gabriele Papalinetti, Raffaella Giancola, Patrizia Accorsi, Paolo Di Bartolomeo, Paolo Sportoletti, Franca Falzetti
Published 2018-08-01

The landscape of BRAF transcript and protein variants in human cancer

by Andrea Marranci, Zhijie Jiang, Marianna Vitiello, Elena Guzzolino, Laura Comelli, Samanta Sarti, Simone Lubrano, Cinzia Franchin, Ileabett Echevarría-Vargas, Andrea Tuccoli, Alberto Mercatanti, Monica Evangelista, Paolo Sportoletti, Giorgio Cozza, Ettore Luzi, Enrico Capobianco, Jessie Villanueva, Giorgio Arrigoni, Giovanni Signore, Silvia Rocchiccioli, Letizia Pitto, Nicholas Tsinoremas, Laura Poliseno
Published 2017-04-01

NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells

by Mauro Di Ianni, Mauro Di Ianni, Stefano Baldoni, Beatrice Del Papa, Patrizia Aureli, Erica Dorillo, Filomena De Falco, Elisa Albi, Emanuela Varasano, Ambra Di Tommaso, Raffaella Giancola, Patrizia Accorsi, Gianluca Rotta, Chiara Rompietti, Estevão Carlos Silva Barcelos, Estevão Carlos Silva Barcelos, Antonio Francesco Campese, Paolo Di Bartolomeo, Isabella Screpanti, Emanuela Rosati, Franca Falzetti, Paolo Sportoletti
Published 2018-04-01

Perspectives and Emotional Experiences of Patients With Chronic Myeloid Leukemia During ENESTPath Clinical Trial and Treatment-Free Remission: Rationale and Protocol of the Italian...

by Lidia Borghi, Gianantonio Rosti, Alessandro Maggi, Massimo Breccia, Eros Di Bona, Alessandra Iurlo, Gaetano La Barba, Paolo Sportoletti, Francesco Albano, Sara Galimberti, Flavia Rivellini, Giovanna Rege Cambrin, Isabella Capodanno, Antonio Cuneo, Massimiliano Bonifacio, Simona Sica, Luca Arcaini, Enrico Capochiani, Claudia Minotto, Fabio Ciceri, Monica Crugnola, Luigi Di Caprio, Sharon Supekar, Chiara Elena, Michele Baccarani, Elena Vegni
Published 2021-05-01

A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis

by Silvia Moretti, Giorgia Renga, Vasilis Oikonomou, Claudia Galosi, Marilena Pariano, Rossana G. Iannitti, Monica Borghi, Matteo Puccetti, Marco De Zuani, Carlo E. Pucillo, Giuseppe Paolicelli, Teresa Zelante, Jean-Christophe Renauld, Oxana Bereshchenko, Paolo Sportoletti, Vincenzina Lucidi, Maria Chiara Russo, Carla Colombo, Ersilia Fiscarelli, Cornelia Lass-Flörl, Fabio Majo, Gabriella Ricciotti, Helmut Ellemunter, Luigi Ratclif, Vincenzo Nicola Talesa, Valerio Napolioni, Luigina Romani
Published 2017-01-01

Prognostic Impact and Risk Factors of Infections in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

by Francesca Romana Mauro, Diana Giannarelli, Andrea Visentin, Gianluigi Reda, Paolo Sportoletti, Anna Maria Frustaci, Annalisa Chiarenza, Stefania Ciolli, Candida Vitale, Luca Laurenti, Lorenzo De Paoli, Roberta Murru, Massimo Gentile, Gian Matteo Rigolin, Luciano Levato, Annamaria Giordano, Giovanni Del Poeta, Caterina Stelitano, Claudia Ielo, Alessandro Noto, Valerio Guarente, Stefano Molica, Marta Coscia, Alessandra Tedeschi, Gianluca Gaidano, Antonio Cuneo, Robin Foà, Maurizio Martelli, Corrado Girmenia, Giuseppe Gentile, Livio Trentin
Published 2021-06-01

NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status

by Stefano Baldoni, Stefano Baldoni, Beatrice Del Papa, Filomena De Falco, Erica Dorillo, Carlo Sorrentino, Chiara Rompietti, Francesco Maria Adamo, Manuel Nogarotto, Debora Cecchini, Elena Mondani, Estevao Carlos Silva Barcelos, Estevao Carlos Silva Barcelos, Lorenzo Moretti, Maria Grazia Mameli, Bianca Fabi, Daniele Sorcini, Arianna Stella, Raffaella Giancola, Francesco Guardalupi, Francesca Ulbar, Sara Plebani, Valerio Guarente, Emanuela Rosati, Marta Di Nicola, Michele Marchioni, Mauro Di Ianni, Mauro Di Ianni, Paolo Sportoletti
Published 2021-05-01