Synergism/complementarity of recombinant adenoviral vectors and other vaccination platforms during induction of protective immunity against malaria

by Ana Paula Morais Martins Almeida, Oscar Bruna-Romero
Published 2011-08-01

Adenovirus Specific Pre-Immunity Induced by Natural Route of Infection Does Not Impair Transduction by Adenoviral Vaccine Vectors in Mice.

by Bruna de Andrade Pereira, Leoneide E Maduro Bouillet, Natalia A Dorigo, Cornel Fraefel, Oscar Bruna-Romero
Published 2015-01-01

Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi.

by Christopher S Eickhoff, Jose R Vasconcelos, Nicole L Sullivan, Azra Blazevic, Oscar Bruna-Romero, Mauricio M Rodrigues, Daniel F Hoft
Published 2011-03-01

Clinical and parasitological protection in a Leishmania infantum-macaque model vaccinated with adenovirus and the recombinant A2 antigen.

by Gabriel Grimaldi, Antonio Teva, Renato Porrozzi, Marcelo A Pinto, Renato S Marchevsky, Maria Gabrielle L Rocha, Miriam S Dutra, Oscar Bruña-Romero, Ana-Paula Fernandes, Ricardo T Gazzinelli
Published 2014-06-01

Subdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.

by Mariana R Dominguez, Eduardo L V Silveira, José Ronnie C de Vasconcelos, Bruna C G de Alencar, Alexandre V Machado, Oscar Bruna-Romero, Ricardo T Gazzinelli, Mauricio M Rodrigues
Published 2011-01-01

Epitope mapping of recombinant Leishmania donovani virulence factor A2 (recLdVFA2) and canine leishmaniasis diagnosis using a derived synthetic bi-epitope.

by Thais Melo Mendes, Eric Henrique Roma, Fernanda Costal-Oliveira, Lucas de Carvalho Dhom-Lemos, Cristina Monerat Toledo-Machado, Oscar Bruna-Romero, Daniella Castanheiras Bartholomeu, Ricardo Toshio Fujiwara, Carlos Chávez-Olórtegui
Published 2017-05-01

A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.

by Isabela Resende Pereira, Glaucia Vilar-Pereira, Virgínia Marques, Andrea Alice da Silva, Bráulia Caetano, Otacilio Cruz Moreira, Alexandre Vieira Machado, Oscar Bruna-Romero, Maurício Martins Rodrigues, Ricardo Tostes Gazzinelli, Joseli Lannes-Vieira
Published 2015-01-01

The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoa...

by Jonatan Ersching, José R Vasconcelos, Camila P Ferreira, Braulia C Caetano, Alexandre V Machado, Oscar Bruna-Romero, Monique A Baron, Ludmila R P Ferreira, Edécio Cunha-Neto, Kenneth L Rock, Ricardo T Gazzinelli, Maurício M Rodrigues
Published 2016-04-01

Recombinant vaccines of a CD4+ T-cell epitope promote efficient control of Paracoccidioides brasiliensis burden by restraining primary organ infection.

by Rodrigo Assunção Holanda, Julián Esteban Muñoz, Lucas Santos Dias, Leandro Buffoni Roque Silva, Julliana Ribeiro Alves Santos, Sthefany Pagliari, Érica Leandro Marciano Vieira, Tatiane Alves Paixão, Carlos Pelleschi Taborda, Daniel Assis Santos, Oscar Bruña-Romero
Published 2017-09-01

Genetic Vaccination against Experimental Infection with Myotropic Parasite Strains of Trypanosoma cruzi

by Adriano Fernando Araújo, Gabriel de Oliveira, Juliana Fraga Vasconcelos, Jonatan Ersching, Mariana Ribeiro Dominguez, José Ronnie Vasconcelos, Alexandre Vieira Machado, Ricardo Tostes Gazzinelli, Oscar Bruna-Romero, Milena Botelho Soares, Mauricio Martins Rodrigues
Published 2014-01-01

Vaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infection.

by Rafael Polidoro Alves Barbosa, Bruno Galvão Filho, Luara Isabela Dos Santos, Policarpo Ademar Sales Junior, Pedro Elias Marques, Rafaela Vaz Sousa Pereira, Denise Carmona Cara, Oscar Bruña-Romero, Maurício Martins Rodrigues, Ricardo Tostes Gazzinelli, Alexandre Vieira Machado
Published 2013-01-01

Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.

by José Ronnie Vasconcelos, Oscar Bruña-Romero, Adriano F Araújo, Mariana R Dominguez, Jonatan Ersching, Bruna C G de Alencar, Alexandre V Machado, Ricardo T Gazzinelli, Karina R Bortoluci, Gustavo P Amarante-Mendes, Marcela F Lopes, Mauricio M Rodrigues
Published 2012-01-01

LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection

by Camila Pontes Ferreira, Camila Pontes Ferreira, Leonardo Moro Cariste, Leonardo Moro Cariste, Fernando Dos Santos Virgílio, Fernando Dos Santos Virgílio, Barbara Ferri Moraschi, Barbara Ferri Moraschi, Caroline Brandão Monteiro, Alexandre M. Vieira Machado, Ricardo Tostes Gazzinelli, Ricardo Tostes Gazzinelli, Oscar Bruna-Romero, Pedro Luiz Menin Ruiz, Daniel Araki Ribeiro, Joseli Lannes-Vieira, Marcela de Freitas Lopes, Mauricio Martins Rodrigues, Mauricio Martins Rodrigues, José Ronnie Carvalho de Vasconcelos, José Ronnie Carvalho de Vasconcelos, José Ronnie Carvalho de Vasconcelos
Published 2017-10-01

Desenvolvimento de vacinas recombinantes contra malária humana e teste in vivo em modelo murino

by Leoneide Erica Maduro Boillet
Published 2009

Desenvolvimento de um modelo de vacinação contra Toxoplasma gondii empregando adenovírus recombinante

by Braulia Costa Caetano
Published 2005

Análise do potencial imunogênico de variantes polimórficas da proteína de ligação ao antígeno Duffy (DBP) do Plasmodium vivax em modelos murinos

by Roberta Bozi da Silva
Published 2013