Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4

by Ombretta Foresti, Annamaria Ruggiano, Hans K Hannibal-Bach, Christer S Ejsing, Pedro Carvalho
Published 2013-07-01

Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells.

by Andrew L Hellewell, Ombretta Foresti, Nicola Gover, Morwenna Y Porter, Eric W Hewitt
Published 2014-01-01

TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes

by Ishier Raote, Maria Ortega-Bellido, António JM Santos, Ombretta Foresti, Chong Zhang, Maria F Garcia-Parajo, Felix Campelo, Vivek Malhotra
Published 2018-03-01

Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion

by Caroline Lekszas, Ombretta Foresti, Ishier Raote, Daniel Liedtke, Eva-Maria König, Indrajit Nanda, Barbara Vona, Peter De Coster, Rita Cauwels, Vivek Malhotra, Thomas Haaf
Published 2020-02-01