Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.

by Olivier Nolan-Stevaux, Wendy Zhong, Stacey Culp, Kathy Shaffer, Joseph Hoover, Dineli Wickramasinghe, Astrid Ruefli-Brasse
Published 2012-01-01

Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment.

by Olivier Nolan-Stevaux, Donato Tedesco, Seamus Ragan, Mikhail Makhanov, Alex Chenchik, Astrid Ruefli-Brasse, Kim Quon, Paul D Kassner
Published 2013-01-01

718 AMG 509, a STEAP1 x CD3 bispecific XmAb® 2+1 immune therapy, exhibits avidity-driven binding and preferential killing of high STEAP1-expressing prostate and Ewing sarcoma cance...

by Cong Li, Gregory Moore, Umesh Muchhal, John Desjarlais, Matthew Bernett, Madeline Fort, Lingming Liang, Tao Osgood, Rodolfo Yabut, Sarav Kaliyaperumal, John Harrold, Jude Canon, Anna Rogojina, Raushan Kurmasheva, Peter Houghton, Olivier Nolan-Stevaux
Published 2020-11-01