Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

by Karen McQuillan, Fatma Gargoum, Mark P. Murphy, Oliver J. McElvaney, Noel G. McElvaney, Emer P. Reeves
Published 2020-07-01

Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis

by Elaine Hayes, Mark P. Murphy, Kerstin Pohl, Niall Browne, Karen McQuillan, Le Er Saw, Clare Foley, Fatma Gargoum, Oliver J. McElvaney, Padraig Hawkins, Cedric Gunaratnam, Noel G. McElvaney, Emer P. Reeves
Published 2020-12-01

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

by Oliver J McElvaney, Brian D Hobbs, Dandi Qiao, Oisín F McElvaney, Matthew Moll, Natalie L McEvoy, Jennifer Clarke, Eoin O'Connor, Seán Walsh, Michael H Cho, Gerard F Curley, Noel G McElvaney
Published 2020-11-01

Corrigendum to ‘A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19’

by Oliver J McElvaney, Brian D Hobbs, Dandi Qiao, Oisín F McElvaney, Matthew Moll, Natalie L McEvoy, Jennifer Clarke, Eoin O'Connor, Sean Walsh, Michael H Cho, Gerard F Curley, Noel G McElvaney
Published 2020-12-01

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease

by Michelle M. White, Patrick Geraghty, Elaine Hayes, Stephen Cox, William Leitch, Bader Alfawaz, Gillian M. Lavelle, Oliver J. McElvaney, Ryan Flannery, Joanne Keenan, Paula Meleady, Michael Henry, Martin Clynes, Cedric Gunaratnam, Noel G. McElvaney, Emer P. Reeves
Published 2017-09-01

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

by Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J. McElvaney, Oisín F. McElvaney, John Bourke, Bairbre McNicholas, John G. Laffey, Noel G. McElvaney, Gerard F. Curley
Published 2021-01-01

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fi...

by Emer P. Reeves, Nessa Banville, Dorothy M. Ryan, Niamh O’Reilly, David A. Bergin, Kerstin Pohl, Kevin Molloy, Oliver J. McElvaney, Khalifah Alsaleh, Ahmed Aljorfi, Osama Kandalaft, Eimear O'Flynn, Patrick Geraghty, Shane J. O’Neill, Noel G. McElvaney
Published 2013-01-01

A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structu...

by Natalie L. McEvoy, Jennifer L. Clarke, Oliver J. Mc Elvaney, Oisin F. Mc Elvaney, Fiona Boland, Deirdre Hyland, Pierce Geoghegan, Karen Donnelly, Oisin Friel, Ailbhe Cullen, Ann M. Collins, Daniel Fraughen, Ignacio Martin-Loeches, Martina Hennessy, John G. Laffey, Noel G. Mc Elvaney, Gerard F. Curley
Published 2021-04-01

Caspase-11 promotes allergic airway inflammation

by Zbigniew Zasłona, Ewelina Flis, Mieszko M. Wilk, Richard G. Carroll, Eva M. Palsson-McDermott, Mark M. Hughes, Ciana Diskin, Kathy Banahan, Dylan G. Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Gunter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J. McElvaney, Kingston H. G. Mills, Ed C. Lavelle, Małgorzata Wygrecka, Emma M. Creagh, Luke A. J. O’Neill
Published 2020-02-01