SERIneALanine Killer: SPT promiscuity inhibits tumour growth via intra-tumoral deoxysphingolipid production

by Mattia Falcone, Oliver D. K. Maddocks
Published 2020-11-01

p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

by Timothy J. Humpton, Andreas K. Hock, Oliver D. K. Maddocks, Karen H. Vousden
Published 2018-12-01

Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans.

by Oliver D K Maddocks, Abigail J Short, Michael S Donnenberg, Scott Bader, David J Harrison
Published 2009-01-01

Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells

by Christiaan F. Labuschagne, Niels J.F. van den Broek, Gillian M. Mackay, Karen H. Vousden, Oliver D.K. Maddocks
Published 2014-05-01

Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour

by Sílvia F. Henriques, Darshan B. Dhakan, Lúcia Serra, Ana Patrícia Francisco, Zita Carvalho-Santos, Célia Baltazar, Ana Paula Elias, Margarida Anjos, Tong Zhang, Oliver D. K. Maddocks, Carlos Ribeiro
Published 2020-08-01

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion [version 2; peer review: 2 approved]

by Lucy A. Oakey, Rachel S. Fletcher, Yasir S. Elhassan, David M. Cartwright, Craig L. Doig, Antje Garten, Alpesh Thakker, Oliver D. K. Maddocks, Tong Zhang, Daniel A. Tennant, Christian Ludwig, Gareth G. Lavery
Published 2019-09-01

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

by Mylène Tajan, Marc Hennequart, Eric C. Cheung, Fabio Zani, Andreas K. Hock, Nathalie Legrave, Oliver D. K. Maddocks, Rachel A. Ridgway, Dimitris Athineos, Alejandro Suárez-Bonnet, Robert L. Ludwig, Laura Novellasdemunt, Nikolaos Angelis, Vivian S. W. Li, Georgios Vlachogiannis, Nicola Valeri, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, Karen Blyth, Owen J. Sansom, Karen H. Vousden
Published 2021-01-01