CD28 between tolerance and autoimmunity: the side effects of animal models [version 1; referees: 2 approved]

by Nicla Porciello, Martina Kunkl, Loretta Tuosto
Published 2018-05-01

Single nucleotide polymorphisms in the 3'UTR of VPAC-1 cooperate in modulating gene expression and impact differently on the interaction with miR525-5p.

by Fabiana Paladini, Nicla Porciello, Giorgio Camilli, Sinem Tuncer, Elisa Cocco, Maria Teresa Fiorillo, Rosa Sorrentino
Published 2014-01-01

CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

by Martina Kunkl, Marta Mastrogiovanni, Marta Mastrogiovanni, Nicla Porciello, Silvana Caristi, Emanuele Monteleone, Stefano Arcieri, Loretta Tuosto
Published 2019-04-01

ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes

by Loretta Tuosto, Martina Kunkl, Nicla Porciello, Marta Mastrogiovanni, Cristina Capuano, Federica Lucantoni, Chiara Moretti, Jenny L. Persson, Jenny L. Persson, Ricciarda Galandrini, Raffaella Buzzetti
Published 2017-04-01

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

by Nicla Porciello, Paola Grazioli, Antonio F. Campese, Martina Kunkl, Silvana Caristi, Marta Mastrogiovanni, Michela Muscolini, Francesca Spadaro, Cédric Favre, Jacques A. Nunès, Aldo Borroto, Balbino Alarcon, Isabella Screpanti, Loretta Tuosto
Published 2018-03-01

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

by Anna-Lisa Lanz, Giulia Masi, Nicla Porciello, André Cohnen, Deborah Cipria, Dheeraj Prakaash, Štefan Bálint, Roberto Raggiaschi, Donatella Galgano, David K. Cole, Marco Lepore, Omer Dushek, Michael L. Dustin, Mark S.P. Sansom, Antreas C. Kalli, Oreste Acuto
Published 2021-07-01

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

by Anna-Lisa Lanz, Giulia Masi, Nicla Porciello, André Cohnen, Deborah Cipria, Dheeraj Prakaash, Štefan Bálint, Roberto Raggiaschi, Donatella Galgano, David K. Cole, Marco Lepore, Omer Dushek, Michael L. Dustin, Mark S.P. Sansom, Antreas C. Kalli, Oreste Acuto
Published 2021-08-01