Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide...

by Lubov S Grigoryeva, Nicholas P Cianciotto
Published 2021-07-01

Legionella pneumophila persists within biofilms formed by Klebsiella pneumoniae, Flavobacterium sp., and Pseudomonas fluorescens under dynamic flow conditions.

by Catherine R Stewart, Viraj Muthye, Nicholas P Cianciotto
Published 2012-01-01

Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane

by Hilary K. Truchan, Harry D. Christman, Richard C. White, Nakisha S. Rutledge, Nicholas P. Cianciotto, Michele S. Swanson
Published 2017-06-01

Phenylalanine hydroxylase from Legionella pneumophila is a thermostable enzyme with a major functional role in pyomelanin synthesis.

by Marte I Flydal, Christa H Chatfield, Huaixin Zheng, Felizza F Gunderson, Oscar Aubi, Nicholas P Cianciotto, Aurora Martinez
Published 2012-01-01

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

by Richard C. White, Felizza F. Gunderson, Jessica Y. Tyson, Katherine H. Richardson, Theo J. Portlock, James A. Garnett, Nicholas P. Cianciotto, Michele S. Swanson
Published 2018-04-01

Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation.

by Saima Rehman, Lubov S Grigoryeva, Katherine H Richardson, Paula Corsini, Richard C White, Rosie Shaw, Theo J Portlock, Benjamin Dorgan, Zeinab S Zanjani, Arianna Fornili, Nicholas P Cianciotto, James A Garnett
Published 2020-05-01

Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System

by Theo J. Portlock, Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. McIntire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James A. Garnett, James A. Garnett
Published 2020-06-01