A method for intuitively extracting macromolecular dynamics from structural disorder

by Nicholas M. Pearce, Piet Gros
Published 2021-09-01

Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b

by Ramon M. van den Bos, Nicholas M. Pearce, Joke Granneman, T. Harma C. Brondijk, Piet Gros
Published 2019-09-01

Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites

by Nicholas M. Pearce, Anthony R. Bradley, Tobias Krojer, Brian D. Marsden, Charlotte M. Deane, Frank von Delft
Published 2017-05-01

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering

by Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T Justin Rettenmaier, José Brandão-Neto, Nicholas M Pearce, Frank von Delft, James A Wells, James S Fraser
Published 2018-06-01

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

by Nicholas M. Pearce, Tobias Krojer, Anthony R. Bradley, Patrick Collins, Radosław P. Nowak, Romain Talon, Brian D. Marsden, Sebastian Kelm, Jiye Shi, Charlotte M. Deane, Frank von Delft
Published 2017-04-01