Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response.

by Jeffrey W Perry, Mohammad Ahmed, Kyeong-Ok Chang, Nicholas J Donato, Hollis D Showalter, Christiane E Wobus
Published 2012-01-01

Small molecule deubiquitinase inhibitors promote macrophage anti-infective capacity.

by Marie-Eve Charbonneau, Marta J Gonzalez-Hernandez, Hollis D Showalter, Nicholas J Donato, Christiane E Wobus, Mary X D O'Riordan
Published 2014-01-01

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth

by Anupama Pal, Michele Dziubinski, Marina Pasca Di Magliano, Diane M. Simeone, Scott Owens, Dafydd Thomas, Luke Peterson, Harish Potu, Moshe Talpaz, Nicholas J. Donato
Published 2018-02-01

Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses.

by Marta J Gonzalez-Hernandez, Anupama Pal, Kofi E Gyan, Marie-Eve Charbonneau, Hollis D Showalter, Nicholas J Donato, Mary O'Riordan, Christiane E Wobus
Published 2014-01-01

Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma

by Harish Potu, Luke F. Peterson, Malathi Kandarpa, Anupama Pal, Hanshi Sun, Alison Durham, Paul W. Harms, Peter C. Hollenhorst, Ugur Eskiocak, Moshe Talpaz, Nicholas J. Donato
Published 2017-02-01