Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

by Nazareno González, Georgina A. Cardama, Georgina A. Cardama, Patricio Chinestrad, Javier Robles-Valero, Javier Robles-Valero, Javier Robles-Valero, Sonia Rodríguez-Fdez, Sonia Rodríguez-Fdez, Sonia Rodríguez-Fdez, L. Francisco Lorenzo-Martín, L. Francisco Lorenzo-Martín, L. Francisco Lorenzo-Martín, Xosé R. Bustelo, Xosé R. Bustelo, Xosé R. Bustelo, Pablo Lorenzano Menna, Pablo Lorenzano Menna, Daniel E. Gomez, Daniel E. Gomez
Published 2020-04-01

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

by L. Francisco Lorenzo-Martín, Natalia Fernández-Parejo, Mauricio Menacho-Márquez, Sonia Rodríguez-Fdez, Javier Robles-Valero, Sonia Zumalave, Salvatore Fabbiano, Gloria Pascual, Juana M. García-Pedrero, Antonio Abad, María C. García-Macías, Nazareno González, Pablo Lorenzano-Menna, Miguel A. Pavón, Rogelio González-Sarmiento, Carmen Segrelles, Jesús M. Paramio, José M. C. Tubío, Juan P. Rodrigo, Salvador A. Benitah, Myriam Cuadrado, Xosé R. Bustelo
Published 2020-09-01

Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies

by Maria B. Garcia-Fabiani, Maria B. Garcia-Fabiani, Santiago Haase, Santiago Haase, Andrea Comba, Andrea Comba, Stephen Carney, Stephen Carney, Brandon McClellan, Brandon McClellan, Kaushik Banerjee, Kaushik Banerjee, Mahmoud S. Alghamri, Mahmoud S. Alghamri, Faisal Syed, Faisal Syed, Padma Kadiyala, Padma Kadiyala, Felipe J. Nunez, Marianela Candolfi, Antonela Asad, Nazareno Gonzalez, Marisa E. Aikins, Marisa E. Aikins, Anna Schwendeman, Anna Schwendeman, James J. Moon, James J. Moon, James J. Moon, Pedro R. Lowenstein, Pedro R. Lowenstein, Maria G. Castro, Maria G. Castro
Published 2021-06-01