Proteomics Reveals the Potential Protective Mechanism of Hydrogen Sulfide on Retinal Ganglion Cells in an Ischemia/Reperfusion Injury Animal Model

by Hanhan Liu, Natarajan Perumal, Caroline Manicam, Karl Mercieca, Verena Prokosch
Published 2020-08-01

Autoantibody Biomarker Discovery in Primary Open Angle Glaucoma Using Serological Proteome Analysis (SERPA)

by Vanessa M. Beutgen, Natarajan Perumal, Norbert Pfeiffer, Franz H. Grus
Published 2019-03-01

Regulation of the HTRA2 Protease Activity by an Inhibitory Antibody-Derived Peptide Ligand and the Influence on HTRA2-Specific Protein Interaction Networks in Retinal Tissues

by Carsten Schmelter, Kristian Nzogang Fomo, Natarajan Perumal, Norbert Pfeiffer, Franz H. Grus
Published 2021-08-01

Characterization of the human aqueous humour proteome: A comparison of the genders.

by Natarajan Perumal, Caroline Manicam, Matthias Steinicke, Sebastian Funke, Norbert Pfeiffer, Franz H Grus
Published 2017-01-01

Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy

by Carsten Schmelter, Kristian Nzogang Fomo, Natarajan Perumal, Caroline Manicam, Katharina Bell, Norbert Pfeiffer, Franz H. Grus
Published 2019-08-01

Bioenergetic shift and actin cytoskeleton remodelling as acute vascular adaptive mechanisms to angiotensin II in murine retina and ophthalmic artery

by Natarajan Perumal, Lars Straßburger, David P. Herzog, Marianne B. Müller, Norbert Pfeiffer, Franz H. Grus, Caroline Manicam
Published 2020-07-01

Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model

by Pia Grotegut, Natarajan Perumal, Sandra Kuehn, Andreas Smit, H. Burkhard Dick, Franz H. Grus, Stephanie C. Joachim
Published 2020-12-01

Comparison of Two Solid-Phase Extraction (SPE) Methods for the Identification and Quantification of Porcine Retinal Protein Markers by LC-MS/MS

by Carsten Schmelter, Sebastian Funke, Jana Treml, Anja Beschnitt, Natarajan Perumal, Caroline Manicam, Norbert Pfeiffer, Franz H. Grus
Published 2018-12-01

An In-Depth View of the Porcine Trabecular Meshwork Proteome

by Sebastian Funke, Vanessa M. Beutgen, Lea Bechter, Carsten Schmelter, Vanessa Zurawski, Natarajan Perumal, Norbert Pfeiffer, Franz H. Grus
Published 2019-05-01

Comparative Quantitative Analysis of Porcine Optic Nerve Head and Retina Subproteomes

by Sebastian Funke, Carsten Schmelter, Sascha D. Markowitsch, Natarajan Perumal, Janis C. Heyne, Katharina Bell, Norbert Pfeiffer, Franz H. Grus
Published 2019-08-01

Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress

by Debapriya Chakraborty, Vanessa Felzen, Christof Hiebel, Elisabeth Stürner, Natarajan Perumal, Caroline Manicam, Elisabeth Sehn, Franz Grus, Uwe Wolfrum, Christian Behl
Published 2019-06-01

Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery

by Jiong Hu, Marco Sisignano, Roman Brecht, Natarajan Perumal, Carlo Angioni, Iris-Sofia Bibli, Beate Fisslthaler, Hartmut Kleinert, Norbert Pfeiffer, Ingrid Fleming, Caroline Manicam
Published 2021-09-01

Longitudinal CSF proteome profiling in mice to uncover the acute and sustained mechanisms of action of rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK)

by David P. Herzog, Natarajan Perumal, Caroline Manicam, Giulia Treccani, Jens Nadig, Milena Rossmanith, Jan Engelmann, Tanja Jene, Annika Hasch, Michael A. van der Kooij, Klaus Lieb, Nils C. Gassen, Franz H. Grus, Marianne B. Müller
Published 2021-11-01