New Hybrids of 4-Amino-2,3-polymethylene-quinoline and <i>p</i>-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Al...

by Galina F. Makhaeva, Nadezhda V. Kovaleva, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Yu. Astakhova, Elena V. Rudakova, Alexey N. Proshin, Igor V. Serkov, Eugene V. Radchenko, Vladimir A. Palyulin, Sergey O. Bachurin, Rudy J. Richardson
Published 2020-08-01

Loss of <i>swiss cheese</i> in Neurons Contributes to Neurodegeneration with Mitochondria Abnormalities, Reactive Oxygen Species Acceleration and Accumulation of Lipid Droplets in...

by Pavel A. Melentev, Elena V. Ryabova, Nina V. Surina, Darya R. Zhmujdina, Artem E. Komissarov, Ekaterina A. Ivanova, Natalia P. Boltneva, Galina F. Makhaeva, Mariana I. Sliusarenko, Andriy S. Yatsenko, Iryna I. Mohylyak, Nataliya P. Matiytsiv, Halyna R. Shcherbata, Svetlana V. Sarantseva
Published 2021-07-01

New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease Treatment

by Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Irina I. Faingold, Darya A. Poletaeva, Yuliya V. Soldatova, Raisa A. Kotelnikova, Igor V. Serkov, Anatoly K. Ustinov, Alexey N. Proshin, Eugene V. Radchenko, Vladimir A. Palyulin, Rudy J. Richardson
Published 2020-12-01

Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System

by Mikhail G. Akimov, Denis S. Kudryavtsev, Elena V. Kryukova, Elena V. Fomina-Ageeva, Stanislav S. Zakharov, Natalia M. Gretskaya, Galina N. Zinchenko, Igor V. Serkov, Galina F. Makhaeva, Natalia P. Boltneva, Nadezhda V. Kovaleva, Olga G. Serebryakova, Sofya V. Lushchekina, Victor A. Palikov, Yulia Palikova, Igor A. Dyachenko, Igor E. Kasheverov, Victor I. Tsetlin, Vladimir V. Bezuglov
Published 2020-02-01

Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands

by Sergey O. Bachurin, Galina F. Makhaeva, Elena F. Shevtsova, Alexey Yu. Aksinenko, Vladimir V. Grigoriev, Pavel N. Shevtsov, Tatiana V. Goreva, Tatiana A. Epishina, Nadezhda V. Kovaleva, Elena A. Pushkareva, Natalia P. Boltneva, Sofya V. Lushchekina, Alexey V. Gabrelyan, Vladimir L. Zamoyski, Lyudmila G. Dubova, Elena V. Rudakova, Vladimir P. Fisenko, Elena V. Bovina, Rudy J. Richardson
Published 2021-09-01