STX‐0119, a novel STAT3 dimerization inhibitor, prevents fibrotic gene expression in a mouse model of kidney fibrosis by regulating Cxcr4 and Ccr1 expression

by Kouki Makitani, Naohisa Ogo, Akira Asai
Published 2020-10-01

Novel multiplexed assay for identifying SH2 domain antagonists of STAT family proteins.

by Kazuyuki Takakuma, Naohisa Ogo, Yutaka Uehara, Susumu Takahashi, Nao Miyoshi, Akira Asai
Published 2013-01-01

Inhibition of STAT3 by Anticancer Drug Bendamustine.

by Kazunori Iwamoto, Yutaka Uehara, Yukie Inoue, Kyoko Taguchi, Daisuke Muraoka, Naohisa Ogo, Kenji Matsuno, Akira Asai
Published 2017-01-01

Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity.

by Hajime Kashima, Fumiyasu Momose, Hiroshi Umehara, Nao Miyoshi, Naohisa Ogo, Daisuke Muraoka, Hiroshi Shiku, Naozumi Harada, Akira Asai
Published 2016-01-01

Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors

by Hideshi Yokoyama, Jun-ichi Sawada, Kohei Sato, Naohisa Ogo, Nanami Kamei, Yoshinobu Ishikawa, Kodai Hara, Akira Asai, Hiroshi Hashimoto
Published 2018-09-01