Prions amplify through degradation of the VPS10P sorting receptor sortilin.

by Keiji Uchiyama, Mitsuru Tomita, Masashi Yano, Junji Chida, Hideyuki Hara, Nandita Rani Das, Anders Nykjaer, Suehiro Sakaguchi
Published 2017-06-01

Mouse-hamster chimeric prion protein (PrP) devoid of N-terminal residues 23-88 restores susceptibility to 22L prions, but not to RML prions in PrP-knockout mice.

by Keiji Uchiyama, Hironori Miyata, Masashi Yano, Yoshitaka Yamaguchi, Morikazu Imamura, Naomi Muramatsu, Nandita Rani Das, Junji Chida, Hideyuki Hara, Suehiro Sakaguchi
Published 2014-01-01

Prion protein protects mice from lethal infection with influenza A viruses.

by Junji Chida, Hideyuki Hara, Masashi Yano, Keiji Uchiyama, Nandita Rani Das, Etsuhisa Takahashi, Hironori Miyata, Yukiko Tomioka, Toshihiro Ito, Hiroshi Kido, Suehiro Sakaguchi
Published 2018-05-01