The Effects of Repeat-Dose Doxorubicin on Cardiovascular Functional Endpoints and Biomarkers in the Telemetry-Equipped Cynomolgus Monkey

by Michael J. Engwall, Nancy Everds, James R. Turk, Hugo M. Vargas
Published 2021-02-01

Common handling procedures conducted in preclinical safety studies result in minimal hepatic gene expression changes in Sprague-Dawley rats.

by Yudong D He, Christine M Karbowski, Jon Werner, Nancy Everds, Chris Di Palma, Yuan Chen, Marnie Higgins-Garn, Sandra Tran, Cynthia A Afshari, Hisham K Hamadeh
Published 2014-01-01

A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity.

by M Ann Mongan, Robert T Dunn, Steven Vonderfecht, Nancy Everds, Guang Chen, Cheng Su, Marnie Higgins-Garn, Yuan Chen, Cynthia A Afshari, Toni L Williamson, Linda Carlock, Christopher Dipalma, Suzanne Moss, Jeanine Bussiere, Charles Qualls, Yudong D He, Hisham K Hamadeh
Published 2010-01-01