Transition from metal-DTH resistance to susceptibility is facilitated by NLRP3 inflammasome signaling induced Th17 reactivity: Implications for orthopedic implants.

by Lauryn Samelko, Marco S Caicedo, Joshua Jacobs, Nadim James Hallab
Published 2019-01-01

The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

by Stefan Landgraeber, Marcus Jäger, Joshua J. Jacobs, Nadim James Hallab
Published 2014-01-01

Cobalt Alloy Implant Debris Induces Inflammation and Bone Loss Primarily through Danger Signaling, Not TLR4 Activation: Implications for DAMP-ening Implant Related Inflammation.

by Lauryn Samelko, Stefan Landgraeber, Kyron McAllister, Joshua Jacobs, Nadim James Hallab
Published 2016-01-01

Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner.

by Lauryn Samelko, Marco Caicedo, Kyron McAllister, Joshua Jacobs, Nadim James Hallab
Published 2021-01-01