MNS1 is essential for spermiogenesis and motile ciliary functions in mice.

by Jian Zhou, Fang Yang, N Adrian Leu, P Jeremy Wang
Published 2012-01-01

STK31/TDRD8, a germ cell-specific factor, is dispensable for reproduction in mice.

by Jian Zhou, N Adrian Leu, Sigrid Eckardt, K John McLaughlin, P Jeremy Wang
Published 2014-01-01

Arginylation-dependent neural crest cell migration is essential for mouse development.

by Satoshi Kurosaka, N Adrian Leu, Fangliang Zhang, Ralph Bunte, Sougata Saha, Junling Wang, Caiying Guo, Wei He, Anna Kashina
Published 2010-03-01

Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1.

by Juan Qian, Hui Zheng, Wei-Chun Huangfu, Jianghuai Liu, Christopher J Carbone, N Adrian Leu, Darren P Baker, Serge Y Fuchs
Published 2011-06-01

The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis.

by Fang Yang, Yong Cheng, Jee Young An, Yong Tae Kwon, Sigrid Eckardt, N Adrian Leu, K John McLaughlin, Peijing Jeremy Wang
Published 2010-11-01

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.

by Seth D Kasowitz, Jun Ma, Stephen J Anderson, N Adrian Leu, Yang Xu, Brian D Gregory, Richard M Schultz, P Jeremy Wang
Published 2018-05-01

Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis.

by Mengcheng Luo, Jian Zhou, N Adrian Leu, Carla M Abreu, Jianle Wang, Montserrat C Anguera, Dirk G de Rooij, Maria Jasin, P Jeremy Wang
Published 2015-01-01

Paternal poly (ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression.

by Motomasa Ihara, Mirella L Meyer-Ficca, N Adrian Leu, Shilpa Rao, Fan Li, Brian D Gregory, Irina A Zalenskaya, Richard M Schultz, Ralph G Meyer
Published 2014-05-01

Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment

by Jennifer C. Chan, Christopher P. Morgan, N. Adrian Leu, Amol Shetty, Yasmine M. Cisse, Bridget M. Nugent, Kathleen E. Morrison, Eldin Jašarević, Weiliang Huang, Nickole Kanyuch, Ali B. Rodgers, Natarajan V. Bhanu, Dara S. Berger, Benjamin A. Garcia, Seth Ament, Maureen Kane, C. Neill Epperson, Tracy L. Bale
Published 2020-03-01

Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

by Sabyasachi Bhattacharya, Kanstantsin V Katlinski, Maximilian Reichert, Shigetsugu Takano, Angela Brice, Bin Zhao, Qiujing Yu, Hui Zheng, Christopher J Carbone, Yuliya V Katlinskaya, N Adrian Leu, Kelly A McCorkell, Satish Srinivasan, Melanie Girondo, Hallgeir Rui, Michael J May, Narayan G Avadhani, Anil K Rustgi, Serge Y Fuchs
Published 2014-03-01