Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo.

by Shweta Joshi, Alok R Singh, Muamera Zulcic, Lei Bao, Karen Messer, Trey Ideker, Janusz Dutkowski, Donald L Durden
Published 2014-01-01

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.

by Shweta Joshi, Alok R Singh, Simon S Wong, Muamera Zulcic, Min Jiang, Annie Pardo, Moises Selman, James S Hagood, Donald L Durden
Published 2017-01-01

PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.

by Alok R Singh, Shweta Joshi, Muamera Zulcic, Michael Alcaraz, Joseph R Garlich, Guillermo A Morales, Yoon J Cho, Lei Bao, Michael L Levy, Robert Newbury, Denise Malicki, Karen Messer, John Crawford, Donald L Durden
Published 2016-01-01