A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

by Claas Wodarczyk, Isaline Rowe, Marco Chiaravalli, Monika Pema, Feng Qian, Alessandra Boletta
Published 2009-09-01

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex

by Monika Pema, Luca Drusian, Marco Chiaravalli, Maddalena Castelli, Qin Yao, Sara Ricciardi, Stefan Somlo, Feng Qian, Stefano Biffo, Alessandra Boletta
Published 2016-03-01

RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope

by Virna Marin, Anna Stornaiuolo, Claudia Piovan, Stefano Corna, Sergio Bossi, Monika Pema, Erica Giuliani, Cinzia Scavullo, Eleonora Zucchelli, Claudio Bordignon, Gian Paolo Rizzardi, Chiara Bovolenta
Published 2016-01-01

Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein

by Eleonora Zucchelli, Monika Pema, Anna Stornaiuolo, Claudia Piovan, Cinzia Scavullo, Erica Giuliani, Sergio Bossi, Stefano Corna, Claudia Asperti, Claudio Bordignon, Gian-Paolo Rizzardi, Chiara Bovolenta
Published 2017-03-01

Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.

by Claas Wodarczyk, Gianfranco Distefano, Isaline Rowe, Massimiliano Gaetani, Barbara Bricoli, Mordi Muorah, Andrea Spitaleri, Valeria Mannella, Piero Ricchiuto, Monika Pema, Maddalena Castelli, Ariel E Casanova, Luca Mollica, Manuela Banzi, Manila Boca, Corinne Antignac, Sophie Saunier, Giovanna Musco, Alessandra Boletta
Published 2010-09-01