Introducing an In Vitro Liver Stability Assay Capable of Predicting the In Vivo Pharmacodynamic Efficacy of siRNAs for IVIVC

by Babak Basiri, Fang Xie, Bin Wu, Sara C. Humphreys, Julie M. Lade, Mai B. Thayer, Pam Yamaguchi, Monica Florio, Brooke M. Rock
Published 2020-09-01

TGF-β prevents phosphate-induced osteogenesis through inhibition of BMP and Wnt/β-catenin pathways.

by Fátima Guerrero, Carmen Herencia, Yolanda Almadén, Julio M Martínez-Moreno, Addy Montes de Oca, María Encarnación Rodriguez-Ortiz, Juan M Diaz-Tocados, Antonio Canalejo, Mónica Florio, Ignacio López, William G Richards, Mariano Rodriguez, Escolástico Aguilera-Tejero, Juan R Muñoz-Castañeda
Published 2014-01-01

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

by Monica Florio, Kannan Gunasekaran, Marina Stolina, Xiaodong Li, Ling Liu, Barbara Tipton, Hossein Salimi-Moosavi, Franklin J. Asuncion, Chaoyang Li, Banghua Sun, Hong Lin Tan, Li Zhang, Chun-Ya Han, Ryan Case, Amy N. Duguay, Mario Grisanti, Jennitte Stevens, James K. Pretorius, Efrain Pacheco, Heidi Jones, Qing Chen, Brian D. Soriano, Jie Wen, Brenda Heron, Frederick W. Jacobsen, Emil Brisan, William G. Richards, Hua Zhu Ke, Michael S. Ominsky
Published 2016-05-01