Mimicking H3 Substrate Arginine in the Design of G9a Lysine Methyltransferase Inhibitors for Cancer Therapy: A Computational Study for Structure-Based Drug Design

by M. Ramya Chandar Charles, Mu-Chun Li, Hsing-Pang Hsieh, Mohane Selvaraj Coumar
Published 2021-02-01

Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer

by Safiulla Basha Syed, Hemant Arya, I-Hsuan Fu, Teng-Kuang Yeh, Latha Periyasamy, Hsing-Pang Hsieh, Mohane Selvaraj Coumar
Published 2017-08-01

Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

by Larance Ronsard, Larance Ronsard, Akhil C. Banerjea, Nilanjana Ganguli, Vivek K. Singh, Kumaravel Mohankumar, Kumaravel Mohankumar, Tripti Rai, Subhashree Sridharan, Subhashree Sridharan, Sankar Pajaniradje, Binod Kumar, Devesh Rai, Suhnrita Chaudhuri, Mohane S. Coumar, Vishnampettai G. Ramachandran
Published 2017-04-01

BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells.

by Chun Hei Antonio Cheung, Wen-Hsing Lin, John Tsu-An Hsu, Tzyh-Chyuan Hour, Teng-Kuang Yeh, Shengkai Ko, Tzu-Wen Lien, Mohane Selvaraj Coumar, Jin-Fen Liu, Wen-Yang Lai, Hui-Yi Shiao, Tian-Ren Lee, Hsing-Pang Hsieh, Jang-Yang Chang
Published 2011-01-01