A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions.

by Mohammed H Cherkaoui-Rbati, Stuart W Paine, Peter Littlewood, Cyril Rauch
Published 2017-01-01

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults...

by Yeka Adoke, Rella Zoleko-Manego, Serge Ouoba, Alfred B. Tiono, Grace Kaguthi, Juvêncio Eduardo Bonzela, Tran Thanh Duong, Alain Nahum, Marielle Bouyou-Akotet, Bernhards Ogutu, Alphonse Ouedraogo, Fiona Macintyre, Andreas Jessel, Bart Laurijssens, Mohammed H. Cherkaoui-Rbati, Cathy Cantalloube, Anne Claire Marrast, Raphaël Bejuit, David White, Timothy N. C. Wells, Florian Wartha, Didier Leroy, Afizi Kibuuka, Ghyslain Mombo-Ngoma, Daouda Ouattara, Irène Mugenya, Bui Quang Phuc, Francis Bohissou, Denise P. Mawili-Mboumba, Fredrick Olewe, Issiaka Soulama, Halidou Tinto, the FALCI Study Group
Published 2021-05-01