Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK.

by Johji Nomura, Nathalie Busso, Annette Ives, Syunsuke Tsujimoto, Mizuho Tamura, Alexander So, Yoshihiro Yamanaka
Published 2013-01-01

Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection...

by Rodney A. Moxley, David H. Francis, Mizuho Tamura, David B. Marx, Kristina Santiago-Mateo, Mojun Zhao
Published 2017-01-01

Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot...

by Sumito Sunagawa, Takashi Shirakura, Noboru Hokama, Chisayo Kozuka, Masato Yonamine, Toyotaka Namba, Satoko Morishima, Sawako Nakachi, Yukiko Nishi, Tomomi Ikema, Shiki Okamoto, Chieko Matsui, Naoki Hase, Mizuho Tamura, Michio Shimabukuro, Hiroaki Masuzaki
Published 2019-01-01

Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.

by Josephe A Honorat, Yuji Nakatsuji, Mikito Shimizu, Makoto Kinoshita, Hisae Sumi-Akamaru, Tsutomu Sasaki, Kazushiro Takata, Toru Koda, Akiko Namba, Kazuya Yamashita, Eri Sanda, Manabu Sakaguchi, Atsushi Kumanogoh, Takashi Shirakura, Mizuho Tamura, Saburo Sakoda, Hideki Mochizuki, Tatsusada Okuno
Published 2017-01-01