Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice.

by Paul M Schroder, Mithun Khattar, Ronghai Deng, Aini Xie, Wenhao Chen, Stanislaw M Stepkowski
Published 2013-01-01

Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under Interleukin-2 deprivation conditions.

by Mithun Khattar, Yoshihiro Miyahara, Paul M Schroder, Aini Xie, Wenhao Chen, Stanislaw M Stepkowski
Published 2014-01-01

Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection.

by Mithun Khattar, Caitlin E Baum, Paul Schroder, Joshua D Breidenbach, Steven T Haller, Wenhao Chen, Stanislaw Stepkowski
Published 2019-01-01